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    PIEZO2 piezo type mechanosensitive ion channel component 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 490554, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PIEZO2provided by VGNC
    Official Full Name
    piezo type mechanosensitive ion channel component 2provided by VGNC
    Primary source
    VGNC:VGNC:44529
    See related
    Ensembl:ENSCAFG00845004756
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PIEZO2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    55
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (76533250..76973897, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (75880977..76321043, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (76564098..77004969, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (76231312..76673520, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (76259881..76700879, complement)

    Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096831 Neighboring gene uncharacterized LOC102152727 Neighboring gene NSF attachment protein gamma Neighboring gene uncharacterized LOC102152771 Neighboring gene uncharacterized LOC111096921 Neighboring gene 60S ribosomal protein L19-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mechanosensitive monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monoatomic cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to mechanical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of mechanical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    piezo-type mechanosensitive ion channel component 2; LOW QUALITY PROTEIN: piezo-type mechanosensitive ion channel component 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051811.1 Reference ROS_Cfam_1.0

      Range
      76533250..76973897 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038672681.1 → XP_038528609.1  piezo-type mechanosensitive ion channel component 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RD19
      Conserved Domains (2) summary
      pfam12166
      Location:2339 → 2748
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1364 → 1596
      PIEZO; Piezo

    2. XM_038672680.1 → XP_038528608.1  piezo-type mechanosensitive ion channel component 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RD19
      Related
      ENSCAFP00845006775.1, ENSCAFT00845008590.1
      Conserved Domains (2) summary
      pfam12166
      Location:2341 → 2750
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1366 → 1598
      PIEZO; Piezo

    3. XM_038672679.1 → XP_038528607.1  piezo-type mechanosensitive ion channel component 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MP51
      Related
      ENSCAFP00845006757.1, ENSCAFT00845008560.1
      Conserved Domains (2) summary
      pfam12166
      Location:2352 → 2761
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1377 → 1609
      PIEZO; Piezo

    4. XM_038672682.1 → XP_038528610.1  piezo-type mechanosensitive ion channel component 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MD04
      Related
      ENSCAFP00845006750.1, ENSCAFT00845008551.1
      Conserved Domains (2) summary
      pfam12166
      Location:2422 → 2831
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1391 → 1623
      PIEZO; Piezo

    RNA

    1. XR_005430406.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049267.1 Alternate UMICH_Zoey_3.1

      Range
      76231312..76673520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038482420.1 → XP_038338348.1  LOW QUALITY PROTEIN: piezo-type mechanosensitive ion channel component 2 isoform X2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

      Range
      76259881..76700879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038607991.1 → XP_038463919.1  piezo-type mechanosensitive ion channel component 2 isoform X3

      Conserved Domains (2) summary
      pfam12166
      Location:2339 → 2748
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1364 → 1596
      PIEZO; Piezo

    2. XM_038607990.1 → XP_038463918.1  piezo-type mechanosensitive ion channel component 2 isoform X2

      Conserved Domains (2) summary
      pfam12166
      Location:2341 → 2750
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1366 → 1598
      PIEZO; Piezo

    3. XM_038607989.1 → XP_038463917.1  piezo-type mechanosensitive ion channel component 2 isoform X1

      Conserved Domains (2) summary
      pfam12166
      Location:2352 → 2761
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1377 → 1609
      PIEZO; Piezo

    4. XM_038607992.1 → XP_038463920.1  piezo-type mechanosensitive ion channel component 2 isoform X4

      Conserved Domains (2) summary
      pfam12166
      Location:2422 → 2831
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1391 → 1623
      PIEZO; Piezo

    RNA

    1. XR_005397165.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

      Range
      76564098..77004969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038543881.1 → XP_038399809.1  piezo-type mechanosensitive ion channel component 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RD19

    2. XM_038543880.1 → XP_038399808.1  piezo-type mechanosensitive ion channel component 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RD19

    3. XM_038543879.1 → XP_038399807.1  piezo-type mechanosensitive ion channel component 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MP51

    4. XM_038543882.1 → XP_038399810.1  piezo-type mechanosensitive ion channel component 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MD04

    RNA

    1. XR_005362693.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      75880977..76321043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038578206.1 → XP_038434134.1  piezo-type mechanosensitive ion channel component 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RD19
      Conserved Domains (2) summary
      pfam12166
      Location:2339 → 2748
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1364 → 1596
      PIEZO; Piezo

    2. XM_038578203.1 → XP_038434131.1  piezo-type mechanosensitive ion channel component 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RD19
      Conserved Domains (2) summary
      pfam12166
      Location:2341 → 2750
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1366 → 1598
      PIEZO; Piezo

    3. XM_038578200.1 → XP_038434128.1  piezo-type mechanosensitive ion channel component 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MP51
      Conserved Domains (2) summary
      pfam12166
      Location:2352 → 2761
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1377 → 1609
      PIEZO; Piezo

    4. XM_038578218.1 → XP_038434146.1  piezo-type mechanosensitive ion channel component 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MD04
      Conserved Domains (2) summary
      pfam12166
      Location:2422 → 2831
      Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain
      pfam15917
      Location:1391 → 1623
      PIEZO; Piezo

    RNA

    1. XR_005380434.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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