HTR3A 5-hydroxytryptamine receptor 3A [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: HTR3Aprovided by VGNC
Official Full Name: 5-hydroxytryptamine receptor 3Aprovided by VGNC
Primary source: VGNC:VGNC:41829
See related: Ensembl:ENSCAFG00845000246
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	5	NC_051809.1 (19345236..19358844, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	5	NC_006587.4 (19248270..19261807, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	5	NC_049226.1 (19357640..19371211, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	5	NC_049265.1 (19409269..19422833, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	5	NC_049746.1 (19311211..19324318, complement)

Chromosome 5 - NC_051809.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data showed that the HTR3A 195 residue L195W can affect receptor agonist potency and efficacy as well as antagonist potency.
Title: Molecular cloning and pharmacological characterization of serotonin 5-HT(3A) receptor subtype in dog.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables extracellular ligand-gated monoatomic ion channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables neurotransmitter receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nervous system process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of membrane potential	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed
located_in postsynaptic membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 5-hydroxytryptamine receptor 3A

Names: 5-hydroxytryptamine type 3A receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.