DUSP13B dual specificity phosphatase 13B [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: DUSP13Bprovided by VGNC
Official Full Name: dual specificity phosphatase 13Bprovided by VGNC
Primary source: VGNC:VGNC:106597
See related: Ensembl:ENSCAFG00845010082
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: DUSP13
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	4	NC_051808.1 (25642971..25656033, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	4	NC_006586.4 (25495596..25508622, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	4	NC_049225.1 (26094302..26107339, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	4	NC_049264.1 (25538140..25546032, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	4	NC_049745.1 (25738781..25751780, complement)

Chromosome 4 - NC_051808.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables MAP kinase phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein tyrosine/serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity protein phosphatase 13B; dual specificity protein phosphatase 13

Names: dual specificity phosphatase 13

XP_005619129.1

EC 3.1.3.16

EC 3.1.3.48

XP_005619130.2

EC 3.1.3.16

EC 3.1.3.48

XP_013968389.1

EC 3.1.3.16

EC 3.1.3.48

XP_022273299.1

EC 3.1.3.16

EC 3.1.3.48

XP_038329283.1

EC 3.1.3.16

EC 3.1.3.48

XP_038329284.1

EC 3.1.3.16

EC 3.1.3.48

XP_038329285.1

EC 3.1.3.16

EC 3.1.3.48

XP_038390358.1

EC 3.1.3.16

EC 3.1.3.48

XP_038390359.1

EC 3.1.3.16

EC 3.1.3.48

XP_038390360.1

EC 3.1.3.16

EC 3.1.3.48

XP_038390361.1

EC 3.1.3.16

EC 3.1.3.48

XP_038390362.1

EC 3.1.3.16

EC 3.1.3.48

XP_038454681.1

EC 3.1.3.16

EC 3.1.3.48

XP_038454682.1

EC 3.1.3.16

EC 3.1.3.48

XP_038454683.1

EC 3.1.3.16

EC 3.1.3.48

XP_038454684.1

EC 3.1.3.16

EC 3.1.3.48

XP_038454685.1

EC 3.1.3.16

EC 3.1.3.48

XP_038518952.1

EC 3.1.3.16

EC 3.1.3.48

XP_038518954.1

EC 3.1.3.16

EC 3.1.3.48

XP_038518955.1

EC 3.1.3.16

EC 3.1.3.48

XP_038518956.1

EC 3.1.3.16

EC 3.1.3.48

XP_038518957.1

EC 3.1.3.16

EC 3.1.3.48

XP_864305.1

EC 3.1.3.16

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001418265.1 → NP_001405194.1 dual specificity protein phosphatase 13B

Status: VALIDATED

Source sequence(s)

JAAUVH010000355

UniProtKB/TrEMBL

A0A8I3RXJ5, A0A8P0T6S4

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051808.1 Reference ROS_Cfam_1.0

Range

25642971..25656033 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038663024.1 → XP_038518952.1 dual specificity protein phosphatase 13 isoform X1

UniProtKB/TrEMBL

A0A8C0NVL5

Conserved Domains (1) summary

cl28904
Location:239 → 402

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038663026.1 → XP_038518954.1 dual specificity protein phosphatase 13 isoform X2

Conserved Domains (1) summary

cd14577
Location:206 → 369

DUSP13B; dual specificity protein phosphatase 13 isoform B
XM_038663027.1 → XP_038518955.1 dual specificity protein phosphatase 13 isoform X3

UniProtKB/TrEMBL

A0A8I3NFY7

Related

ENSCAFP00845013806.1, ENSCAFT00845017727.1

Conserved Domains (1) summary

cl28904
Location:149 → 312

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038663028.1 → XP_038518956.1 dual specificity protein phosphatase 13 isoform X4

Related

ENSCAFP00845013858.1, ENSCAFT00845017791.1

Conserved Domains (1) summary

cl28904
Location:146 → 309

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038663029.1 → XP_038518957.1 dual specificity protein phosphatase 13 isoform X5

UniProtKB/TrEMBL

A0A8C0KSQ1, A0A8C0P1G6

Conserved Domains (1) summary

cd14580
Location:38 → 182

DUSP13A; dual specificity protein phosphatase 13 isoform A

RNA

XR_005425570.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

NC_049264.1 Alternate UMICH_Zoey_3.1

Range

25538140..25546032 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038473356.1 → XP_038329284.1 dual specificity protein phosphatase 13 isoform X6
XM_038473357.1 → XP_038329285.1 dual specificity protein phosphatase 13 isoform X7
XM_038473355.1 → XP_038329283.1 dual specificity protein phosphatase 13 isoform X4

Conserved Domains (1) summary

cl28904
Location:146 → 309

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049745.1 Alternate UNSW_CanFamBas_1.0

Range

25738781..25751780 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038598753.1 → XP_038454681.1 dual specificity protein phosphatase 13 isoform X1

Conserved Domains (2) summary

cd14577
Location:239 → 402

DUSP13B; dual specificity protein phosphatase 13 isoform B

cl28904
Location:21 → 72

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038598754.1 → XP_038454682.1 dual specificity protein phosphatase 13 isoform X2

Conserved Domains (1) summary

cd14577
Location:206 → 369

DUSP13B; dual specificity protein phosphatase 13 isoform B
XM_038598755.1 → XP_038454683.1 dual specificity protein phosphatase 13 isoform X3
XM_038598756.1 → XP_038454684.1 dual specificity protein phosphatase 13 isoform X4

Conserved Domains (1) summary

cl28904
Location:146 → 309

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038598757.1 → XP_038454685.1 dual specificity protein phosphatase 13 isoform X5

Conserved Domains (1) summary

cd14580
Location:38 → 182

DUSP13A; dual specificity protein phosphatase 13 isoform A

RNA

XR_005392479.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049225.1 Alternate UU_Cfam_GSD_1.0

Range

26094302..26107339 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038534430.1 → XP_038390358.1 dual specificity protein phosphatase 13 isoform X1

UniProtKB/TrEMBL

A0A8C0NVL5

Conserved Domains (1) summary

cl28904
Location:239 → 402

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038534431.1 → XP_038390359.1 dual specificity protein phosphatase 13 isoform X2

Conserved Domains (1) summary

cd14577
Location:206 → 369

DUSP13B; dual specificity protein phosphatase 13 isoform B
XM_038534432.1 → XP_038390360.1 dual specificity protein phosphatase 13 isoform X3

UniProtKB/TrEMBL

A0A8I3NFY7

Conserved Domains (1) summary

cl28904
Location:149 → 312

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038534433.1 → XP_038390361.1 dual specificity protein phosphatase 13 isoform X4

UniProtKB/TrEMBL

A0A8C0Q0H7, A0A8I3RXJ5, A0A8P0T6S4

Conserved Domains (1) summary

cl28904
Location:146 → 309

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_038534434.1 → XP_038390362.1 dual specificity protein phosphatase 13 isoform X5

UniProtKB/TrEMBL

A0A8C0KSQ1, A0A8C0P1G6

Conserved Domains (1) summary

cd14580
Location:38 → 182

DUSP13A; dual specificity protein phosphatase 13 isoform A

RNA

XR_005357973.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

25495596..25508622 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_014112914.3 → XP_013968389.1 dual specificity protein phosphatase 13 isoform X1

Conserved Domains (2) summary

cd14577
Location:239 → 402

DUSP13B; dual specificity protein phosphatase 13 isoform B

cl28904
Location:21 → 72

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_005619073.4 → XP_005619130.2 dual specificity protein phosphatase 13 isoform X2

Conserved Domains (1) summary

cd14577
Location:206 → 369

DUSP13B; dual specificity protein phosphatase 13 isoform B
XM_022417591.2 → XP_022273299.1 dual specificity protein phosphatase 13 isoform X3

UniProtKB/TrEMBL

A0A8P0NGS4

Conserved Domains (1) summary

cd00127
Location:166 → 309

DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
XM_005619072.4 → XP_005619129.1 dual specificity protein phosphatase 13 isoform X4

Conserved Domains (1) summary

cl28904
Location:146 → 309

PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
XM_859212.5 → XP_864305.1 dual specificity protein phosphatase 13 isoform X5

UniProtKB/TrEMBL

A0A8C0KSQ1, A0A8C0P1G6

Conserved Domains (1) summary

cd14580
Location:38 → 182

DUSP13A; dual specificity protein phosphatase 13 isoform A