LOC486307 piwi-like protein 1 [Canis lupus familiaris (dog)] - Gene

Summary

Gene symbol: LOC486307
Gene description: piwi-like protein 1
See related: Ensembl:ENSCAFG00845020348
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: PIWIL3
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Genomic context

Location:: chromosome: 26

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	26	NC_051830.1 (17379223..17407390, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	26	NC_006608.4 (18739185..18766762)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	26	NC_049247.1 (17387029..17414680, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	26	NC_049286.1 (18948385..18974803)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	26	NC_049767.1 (17369622..17397271, complement)

Chromosome 26 - NC_051830.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables piRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in P granule	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: piwi-like protein 3; piwi-like protein 1

Names: piwi-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051830.1 Reference ROS_Cfam_1.0

Range

17379223..17407390 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038436166.1 → XP_038292094.1 piwi-like protein 1 isoform X1

UniProtKB/TrEMBL

A0A8C0TW56

Related

ENSCAFP00845028263.1, ENSCAFT00845036115.1

Conserved Domains (3) summary

cd02845
Location:344 → 474

PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...

cd04658
Location:482 → 926

Piwi_piwi-like_Euk; PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of related ...

cl00301
Location:170 → 235

PAZ; PAZ domain, named PAZ after the proteins Piwi Argonaut and Zwille. PAZ is found in two families of proteins that are essential components of RNA-mediated gene-silencing pathways, including RNA interference, the piwi and Dicer families. PAZ functions as a ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049286.1 Alternate UMICH_Zoey_3.1

Range

18948385..18974803

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038512597.1 → XP_038368525.1 piwi-like protein 1 isoform X2

Conserved Domains (3) summary

cd02845
Location:317 → 447

PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...

cd04658
Location:455 → 899

Piwi_piwi-like_Euk; PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of related ...

cl00301
Location:143 → 208

PAZ; PAZ domain, named PAZ after the proteins Piwi Argonaut and Zwille. PAZ is found in two families of proteins that are essential components of RNA-mediated gene-silencing pathways, including RNA interference, the piwi and Dicer families. PAZ functions as a ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049767.1 Alternate UNSW_CanFamBas_1.0

Range

17369622..17397271 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038638762.1 → XP_038494690.1 piwi-like protein 1 isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049247.1 Alternate UU_Cfam_GSD_1.0

Range

17387029..17414680 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038576091.1 → XP_038432019.1 piwi-like protein 1 isoform X4

UniProtKB/TrEMBL

A0A8C0TW56

Conserved Domains (3) summary

cd02845
Location:317 → 447

PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...

cd04658
Location:455 → 899

Piwi_piwi-like_Euk; PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of related ...

cl00301
Location:143 → 208

PAZ; PAZ domain, named PAZ after the proteins Piwi Argonaut and Zwille. PAZ is found in two families of proteins that are essential components of RNA-mediated gene-silencing pathways, including RNA interference, the piwi and Dicer families. PAZ functions as a ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

18739185..18766762

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038459211.1 → XP_038315139.1 piwi-like protein 1 isoform X5

UniProtKB/TrEMBL

A0A8C0TSJ7

Conserved Domains (3) summary

cd02845
Location:317 → 402

PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...

cd04658
Location:467 → 882

Piwi_piwi-like_Euk; PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of related ...

cl00301
Location:143 → 208

PAZ; PAZ domain, named PAZ after the proteins Piwi Argonaut and Zwille. PAZ is found in two families of proteins that are essential components of RNA-mediated gene-silencing pathways, including RNA interference, the piwi and Dicer families. PAZ functions as a ...