UNC5CL unc-5 family C-terminal like [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: UNC5CLprovided by VGNC
Official Full Name: unc-5 family C-terminal likeprovided by VGNC
Primary source: VGNC:VGNC:48142
See related: Ensembl:ENSCAFG00845014744
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	12	NC_051816.1 (10261886..10274171, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	12	NC_006594.4 (9812647..9824932, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	12	NC_049233.1 (9970656..9982941, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	12	NC_049272.1 (9794206..9806475, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	12	NC_049753.1 (9876010..9888295, complement)

Chromosome 12 - NC_051816.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables netrin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in netrin-activated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of JNK cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: UNC5C-like protein

Names: unc-5 homolog C-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051816.1 Reference ROS_Cfam_1.0

Range

10261886..10274171 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038683447.1 → XP_038539375.1 UNC5C-like protein isoform X2

UniProtKB/TrEMBL

A0A8C0TJ00

Conserved Domains (3) summary

pfam00791
Location:33 → 110

ZU5; ZU5 domain

pfam17217
Location:168 → 282

UPA; UPA domain

cl14633
Location:333 → 413

DD; Death Domain Superfamily of protein-protein interaction domains
XM_038683446.1 → XP_038539374.1 UNC5C-like protein isoform X1

UniProtKB/TrEMBL

A0A8C0TJ00, A0A8I3NPU8, A0A8P0N4Q7

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains
XM_038683445.1 → XP_038539373.1 UNC5C-like protein isoform X1

UniProtKB/TrEMBL

A0A8C0TJ00, A0A8I3NPU8, A0A8P0N4Q7

Related

ENSCAFP00845020775.1, ENSCAFT00845026354.1

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UMICH_Zoey_3.1

Genomic

NC_049272.1 Alternate UMICH_Zoey_3.1

Range

9794206..9806475 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038491760.1 → XP_038347688.1 UNC5C-like protein isoform X2
XM_038491759.1 → XP_038347687.1 UNC5C-like protein isoform X1
XM_038491758.1 → XP_038347686.1 UNC5C-like protein isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049753.1 Alternate UNSW_CanFamBas_1.0

Range

9876010..9888295 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038617854.1 → XP_038473782.1 UNC5C-like protein isoform X2

Conserved Domains (3) summary

pfam00791
Location:33 → 110

ZU5; ZU5 domain

pfam17217
Location:168 → 282

UPA; UPA domain

cl14633
Location:333 → 413

DD; Death Domain Superfamily of protein-protein interaction domains
XM_038617853.1 → XP_038473781.1 UNC5C-like protein isoform X1

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains
XM_038617852.1 → XP_038473780.1 UNC5C-like protein isoform X1

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049233.1 Alternate UU_Cfam_GSD_1.0

Range

9970656..9982941 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038553985.1 → XP_038409913.1 UNC5C-like protein isoform X2

UniProtKB/TrEMBL

A0A8C0TJ00

Conserved Domains (3) summary

pfam00791
Location:33 → 110

ZU5; ZU5 domain

pfam17217
Location:168 → 282

UPA; UPA domain

cl14633
Location:333 → 413

DD; Death Domain Superfamily of protein-protein interaction domains
XM_038553984.1 → XP_038409912.1 UNC5C-like protein isoform X1

UniProtKB/TrEMBL

A0A8C0RE83, A0A8C0TJ00

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains
XM_038553983.1 → XP_038409911.1 UNC5C-like protein isoform X1

UniProtKB/TrEMBL

A0A8C0RE83, A0A8C0TJ00

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

9812647..9824932 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005627298.4 → XP_005627355.1 UNC5C-like protein isoform X2

UniProtKB/TrEMBL

A0A8C0TJ00

Conserved Domains (3) summary

pfam00791
Location:33 → 110

ZU5; ZU5 domain

pfam17217
Location:168 → 282

UPA; UPA domain

cl14633
Location:333 → 413

DD; Death Domain Superfamily of protein-protein interaction domains
XM_538907.6 → XP_538907.2 UNC5C-like protein isoform X1

See identical proteins and their annotated locations for XP_538907.2

UniProtKB/TrEMBL

A0A8C0TJ00, A0A8I3NPU8, A0A8P0N4Q7

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains
XM_014118421.3 → XP_013973896.1 UNC5C-like protein isoform X1

UniProtKB/TrEMBL

A0A8C0TJ00, A0A8I3NPU8, A0A8P0N4Q7

Conserved Domains (3) summary

pfam00791
Location:108 → 185

ZU5; ZU5 domain

pfam17217
Location:243 → 357

UPA; UPA domain

cl14633
Location:408 → 488

DD; Death Domain Superfamily of protein-protein interaction domains