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    ATG2B autophagy related 2B [ Canis lupus familiaris (dog) ]

    Gene ID: 480428, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ATG2Bprovided by VGNC
    Official Full Name
    autophagy related 2Bprovided by VGNC
    Primary source
    VGNC:VGNC:38222
    See related
    Ensembl:ENSCAFG00845003608
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (65311353..65382558, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (64555847..64626693, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (65369420..65440283, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (64984413..65055244, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (65045745..65116666, complement)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene bradykinin receptor B2 Neighboring gene bradykinin receptor B1 Neighboring gene GSK3B interacting protein Neighboring gene adenylate kinase 7 Neighboring gene uncharacterized LOC119872922 Neighboring gene uncharacterized LOC111097154

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol-3-phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagy of mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in piecemeal microautophagy of the nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in reticulophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in phagophore assembly site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    autophagy-related protein 2 homolog B; LOW QUALITY PROTEIN: autophagy-related protein 2 homolog B
    Names
    ATG2 autophagy related 2 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      65311353..65382558 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038674573.1 → XP_038530501.1  autophagy-related protein 2 homolog B isoform X2

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      COG5043
      Location:17 → 234
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
      pfam09333
      Location:1997 → 2091
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:16 → 105
      Chorein_N; N-terminal region of Chorein or VPS13

    2. XM_038674574.1 → XP_038530502.1  autophagy-related protein 2 homolog B isoform X3

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      COG5043
      Location:17 → 234
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
      pfam09333
      Location:1997 → 2091
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:16 → 105
      Chorein_N; N-terminal region of Chorein or VPS13

    3. XM_038674576.1 → XP_038530504.1  autophagy-related protein 2 homolog B isoform X4

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      COG5043
      Location:17 → 234
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
      pfam09333
      Location:1978 → 2072
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:16 → 105
      Chorein_N; N-terminal region of Chorein or VPS13

    4. XM_038674572.1 → XP_038530500.1  autophagy-related protein 2 homolog B isoform X1

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      COG5043
      Location:17 → 234
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
      pfam09333
      Location:1998 → 2092
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:16 → 105
      Chorein_N; N-terminal region of Chorein or VPS13

    5. XM_038674575.1 → XP_038530503.1  autophagy-related protein 2 homolog B isoform X6

      UniProtKB/TrEMBL
      A0A8C0KN88, A0A8I3MR37
      Related
      ENSCAFP00845005157.1, ENSCAFT00845006481.1
      Conserved Domains (3) summary
      COG5043
      Location:17 → 234
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
      pfam09333
      Location:1979 → 2073
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:16 → 105
      Chorein_N; N-terminal region of Chorein or VPS13

    6. XM_038674577.1 → XP_038530505.1  autophagy-related protein 2 homolog B isoform X5

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (2) summary
      COG5043
      Location:17 → 234
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
      pfam12624
      Location:16 → 105
      Chorein_N; N-terminal region of Chorein or VPS13

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      64984413..65055244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038484150.1 → XP_038340078.1  autophagy-related protein 2 homolog B isoform X2

    2. XM_038484151.1 → XP_038340079.1  autophagy-related protein 2 homolog B isoform X3

    3. XM_038484153.1 → XP_038340081.1  autophagy-related protein 2 homolog B isoform X4

    4. XM_038484149.1 → XP_038340077.1  autophagy-related protein 2 homolog B isoform X1

    5. XM_038484152.1 → XP_038340080.1  autophagy-related protein 2 homolog B isoform X6

    6. XM_038484154.1 → XP_038340082.1  autophagy-related protein 2 homolog B isoform X5

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      65045745..65116666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038609762.1 → XP_038465690.1  LOW QUALITY PROTEIN: autophagy-related protein 2 homolog B isoform X6

      Conserved Domains (3) summary
      COG5043
      Location:17 → 234
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
      pfam09333
      Location:1979 → 2073
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:16 → 105
      Chorein_N; N-terminal region of Chorein or VPS13

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      65369420..65440283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038545658.1 → XP_038401586.1  autophagy-related protein 2 homolog B isoform X2

      UniProtKB/TrEMBL
      A0A8C0KN88

    2. XM_038545659.1 → XP_038401587.1  autophagy-related protein 2 homolog B isoform X3

      UniProtKB/TrEMBL
      A0A8C0KN88

    3. XM_038545661.1 → XP_038401589.1  autophagy-related protein 2 homolog B isoform X4

      UniProtKB/TrEMBL
      A0A8C0KN88

    4. XM_038545657.1 → XP_038401585.1  autophagy-related protein 2 homolog B isoform X1

      UniProtKB/TrEMBL
      A0A8C0KN88

    5. XM_038545660.1 → XP_038401588.1  autophagy-related protein 2 homolog B isoform X6

      UniProtKB/TrEMBL
      A0A8C0KN88, A0A8C0MWZ1, A0A8P0SLX5

    6. XM_038545662.1 → XP_038401590.1  autophagy-related protein 2 homolog B isoform X5

      UniProtKB/TrEMBL
      A0A8C0KN88

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      64555847..64626693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014116145.3 → XP_013971620.1  autophagy-related protein 2 homolog B isoform X2

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      pfam09333
      Location:1997 → 2091
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:11 → 105
      Chorein_N; N-terminal region of Chorein or VPS13
      pfam13329
      Location:1238 → 1358
      ATG2_CAD; Autophagy-related protein 2 CAD motif

    2. XM_022422358.2 → XP_022278066.1  autophagy-related protein 2 homolog B isoform X3

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      pfam09333
      Location:1997 → 2091
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:11 → 106
      Chorein_N; N-terminal region of Chorein or VPS13
      cl25572
      Location:17 → 234
      VPS13; Vacuolar sorting-associated protein 13, N-terminal

    3. XM_022422359.2 → XP_022278067.1  autophagy-related protein 2 homolog B isoform X4

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      pfam09333
      Location:1978 → 2072
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:11 → 106
      Chorein_N; N-terminal region of Chorein or VPS13
      cl25572
      Location:17 → 234
      VPS13; Vacuolar sorting-associated protein 13, N-terminal

    4. XM_014116144.3 → XP_013971619.1  autophagy-related protein 2 homolog B isoform X1

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (3) summary
      pfam09333
      Location:1998 → 2092
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:11 → 105
      Chorein_N; N-terminal region of Chorein or VPS13
      pfam13329
      Location:1239 → 1359
      ATG2_CAD; Autophagy-related protein 2 CAD motif

    5. XM_537549.6 → XP_537549.3  autophagy-related protein 2 homolog B isoform X6

      UniProtKB/TrEMBL
      A0A8C0KN88, A0A8C0MWZ1, A0A8P0SLX5
      Conserved Domains (3) summary
      pfam09333
      Location:1979 → 2073
      ATG_C; Autophagy-related protein C terminal domain
      pfam12624
      Location:11 → 105
      Chorein_N; N-terminal region of Chorein or VPS13
      pfam13329
      Location:1239 → 1359
      ATG2_CAD; Autophagy-related protein 2 CAD motif

    6. XM_014116146.3 → XP_013971621.1  autophagy-related protein 2 homolog B isoform X5

      UniProtKB/TrEMBL
      A0A8C0KN88
      Conserved Domains (2) summary
      pfam12624
      Location:11 → 105
      Chorein_N; N-terminal region of Chorein or VPS13
      pfam13329
      Location:1239 → 1359
      ATG2_CAD; Autophagy-related protein 2 CAD motif
    Nucleotide Protein
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