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    BHMT betaine--homocysteine S-methyltransferase [ Canis lupus familiaris (dog) ]

    Gene ID: 479171, updated on 5-Mar-2024

    Summary

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    Official Symbol
    BHMTprovided by VGNC
    Official Full Name
    betaine--homocysteine S-methyltransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:38447
    See related
    Ensembl:ENSCAFG00845007347
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See BHMT in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (27652772..27671416, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (28973220..28991599, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (27851113..27869743, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (27591867..27610507, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (27570180..27588856, complement)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC119881441 Neighboring gene 40S ribosomal protein S8-like Neighboring gene proteasome maturation protein-like Neighboring gene betaine--homocysteine S-methyltransferase 2 Neighboring gene dimethylglycine dehydrogenase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables betaine-homocysteine S-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methionine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    betaine--homocysteine S-methyltransferase 1
    Names
    betaine-homocysteine methyltransferase
    XP_005618234.1
    XP_038327474.1
    XP_038327475.1
    XP_038388402.1
    XP_038388403.1
    XP_038452689.1
    XP_038452690.1
    XP_038516897.1
    XP_038516898.1
    XP_536313.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      27652772..27671416 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038660969.1 → XP_038516897.1  betaine--homocysteine S-methyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NM34, A0A8C0QDD7, A0A8I3MUM0
      Related
      ENSCAFP00845010127.1, ENSCAFT00845012994.1
      Conserved Domains (1) summary
      pfam02574
      Location:23 → 312
      S-methyl_trans; Homocysteine S-methyltransferase

    2. XM_038660970.1 → XP_038516898.1  betaine--homocysteine S-methyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NM34, A0A8C0NUX3, A0A8I3RTW5
      Related
      ENSCAFP00845010149.1, ENSCAFT00845013027.1
      Conserved Domains (1) summary
      pfam02574
      Location:13 → 302
      S-methyl_trans; Homocysteine S-methyltransferase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      27591867..27610507 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038471546.1 → XP_038327474.1  betaine--homocysteine S-methyltransferase 1 isoform X1

      Conserved Domains (1) summary
      pfam02574
      Location:23 → 312
      S-methyl_trans; Homocysteine S-methyltransferase

    2. XM_038471547.1 → XP_038327475.1  betaine--homocysteine S-methyltransferase 1 isoform X2

      Conserved Domains (1) summary
      pfam02574
      Location:13 → 302
      S-methyl_trans; Homocysteine S-methyltransferase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      27570180..27588856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038596761.1 → XP_038452689.1  betaine--homocysteine S-methyltransferase 1 isoform X1

      Conserved Domains (1) summary
      pfam02574
      Location:23 → 312
      S-methyl_trans; Homocysteine S-methyltransferase

    2. XM_038596762.1 → XP_038452690.1  betaine--homocysteine S-methyltransferase 1 isoform X2

      Conserved Domains (1) summary
      pfam02574
      Location:13 → 302
      S-methyl_trans; Homocysteine S-methyltransferase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      27851113..27869743 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038532474.1 → XP_038388402.1  betaine--homocysteine S-methyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LQV9, A0A8C0NM34

    2. XM_038532475.1 → XP_038388403.1  betaine--homocysteine S-methyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NM34

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      28973220..28991599 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_536313.7 → XP_536313.2  betaine--homocysteine S-methyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NM34, A0A8C0QDD7, A0A8I3MUM0
      Conserved Domains (1) summary
      pfam02574
      Location:23 → 312
      S-methyl_trans; Homocysteine S-methyltransferase

    2. XM_005618177.4 → XP_005618234.1  betaine--homocysteine S-methyltransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NM34, A0A8C0NUX3, A0A8I3RTW5
      Conserved Domains (1) summary
      pfam02574
      Location:13 → 302
      S-methyl_trans; Homocysteine S-methyltransferase
    Nucleotide Protein
    Heading Accession and Version

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