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    NELFE negative elongation factor complex member E [ Canis lupus familiaris (dog) ]

    Gene ID: 474854, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NELFEprovided by VGNC
    Official Full Name
    negative elongation factor complex member Eprovided by VGNC
    Primary source
    VGNC:VGNC:111590
    See related
    Ensembl:ENSCAFG00845013870
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    RDBP
    Orthologs
    human mouse all
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    Genomic context

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    See NELFE in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (1548568..1554700, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (1541468..1547598, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (1539542..1546943, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (1405843..1411974, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (1474213..1480345, complement)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 12 Neighboring gene complement C2 Neighboring gene complement factor B Neighboring gene SKI2 subunit of superkiller complex Neighboring gene decapping exoribonuclease

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NELF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    negative elongation factor E; LOW QUALITY PROTEIN: negative elongation factor E
    Names
    RD RNA binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      1548568..1554700 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038683069.1 → XP_038538997.1  negative elongation factor E

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Related
      ENSCAFP00845019493.1, ENSCAFT00845024782.1
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    2. XM_038683070.1 → XP_038538998.1  negative elongation factor E

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    3. XM_038683071.1 → XP_038538999.1  negative elongation factor E

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Related
      ENSCAFP00845019501.1, ENSCAFT00845024793.1
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      1405843..1411974 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038491394.1 → XP_038347322.1  LOW QUALITY PROTEIN: negative elongation factor E

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      1474213..1480345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038617484.1 → XP_038473412.1  negative elongation factor E

      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    2. XM_038617485.1 → XP_038473413.1  negative elongation factor E

      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    3. XM_038617486.1 → XP_038473414.1  negative elongation factor E

      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      1539542..1546943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038553608.1 → XP_038409536.1  negative elongation factor E

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    2. XM_038553610.1 → XP_038409538.1  negative elongation factor E

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    3. XM_038553609.1 → XP_038409537.1  negative elongation factor E

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      1541468..1547598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_532087.7 → XP_532087.1  negative elongation factor E

      See identical proteins and their annotated locations for XP_532087.1

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    2. XM_005627169.4 → XP_005627226.1  negative elongation factor E

      See identical proteins and their annotated locations for XP_005627226.1

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    3. XM_038678708.1 → XP_038534636.1  negative elongation factor E

      UniProtKB/TrEMBL
      A0A8C0JHL7, A0A8C0PNU3, A0A8I3NRP4, A0A8I3NSF7, A0A8P0T8L2
      Conserved Domains (1) summary
      cd12305
      Location:252 → 326
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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