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    PLA2G6 phospholipase A2 group VI [ Pan troglodytes (chimpanzee) ]

    Gene ID: 470208, updated on 3-Apr-2024

    Summary

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    Official Symbol
    PLA2G6provided by VGNC
    Official Full Name
    phospholipase A2 group VIprovided by VGNC
    Primary source
    VGNC:VGNC:9925
    Locus tag
    CK820_G0027648
    See related
    Ensembl:ENSPTRG00000014362
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 22
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 23 NC_086016.1 (40120565..40201189, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 22 NC_072420.1 (33152960..33233589, complement)

    Chromosome 23 - NC_086016.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134809690 Neighboring gene solute carrier family 16 member 8 Neighboring gene BAR/IMD domain containing adaptor protein 2 like 2 Neighboring gene MAF bZIP transcription factor F Neighboring gene transmembrane protein 184B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium-independent phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cardiolipin acyl-chain remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    85/88 kDa calcium-independent phospholipase A2
    Names
    85 kDa calcium-independent phospholipase A2
    phospholipase A2, group VI (cytosolic, calcium-independent)
    XP_003317276.1
    XP_003317277.1
    XP_009436653.1
    XP_009436654.1
    XP_009436656.1
    XP_009436657.1
    XP_009436659.1
    XP_016794647.1
    XP_016794648.1
    XP_016794650.1
    XP_024208692.1
    XP_024208693.1
    XP_024208696.1
    XP_054531726.1
    XP_054531727.1
    XP_054531728.1
    XP_063663891.1
    XP_063663892.1
    XP_063663893.1
    XP_063663894.1
    XP_063663895.1
    XP_063663896.1
    XP_063663897.1
    XP_063663898.1
    XP_063663899.1
    XP_063663900.1
    XP_063663901.1
    XP_063663902.1
    XP_063663903.1
    XP_063663904.1
    XP_063663905.1
    XP_063663906.1
    XP_063663907.1
    XP_063663908.1
    XP_063663909.1
    XP_063663910.1
    XP_063663911.1
    XP_063663912.1
    XP_063663913.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      40120565..40201189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009438384.5 → XP_009436659.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

      Conserved Domains (4) summary
      cd07212
      Location:453 → 766
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:241 → 397
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:318 → 407
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:313 → 341
      ANK; ANK repeat [structural motif]

    2. XM_009438378.5 → XP_009436653.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

      Conserved Domains (4) summary
      cd07212
      Location:507 → 820
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:312 → 430
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:318 → 407
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:313 → 341
      ANK; ANK repeat [structural motif]

    3. XM_063807828.1 → XP_063663898.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    4. XM_063807825.1 → XP_063663895.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9

    5. XM_009438379.5 → XP_009436654.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      See identical proteins and their annotated locations for XP_009436654.1

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4
      Related
      ENSPTRP00000024738.4
      Conserved Domains (3) summary
      cd07212
      Location:480 → 793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285 → 403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]

    6. XM_063807842.1 → XP_063663912.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

    7. XM_063807836.1 → XP_063663906.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    8. XM_063807837.1 → XP_063663907.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    9. XM_054675752.2 → XP_054531727.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9

    10. XM_016939159.4 → XP_016794648.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4
      Conserved Domains (3) summary
      cd07212
      Location:480 → 793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285 → 403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]

    11. XM_063807830.1 → XP_063663900.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    12. XM_063807824.1 → XP_063663894.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9

    13. XM_016939158.4 → XP_016794647.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4
      Conserved Domains (3) summary
      cd07212
      Location:480 → 793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285 → 403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]

    14. XM_063807839.1 → XP_063663909.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

    15. XM_063807827.1 → XP_063663897.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9

    16. XM_063807822.1 → XP_063663892.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4

    17. XM_024352925.3 → XP_024208693.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9
      Conserved Domains (4) summary
      cd07212
      Location:426 → 739
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:214 → 370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:350 → 395
      Ank_4; Ankyrin repeats (many copies)

    18. XM_009438381.5 → XP_009436656.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      See identical proteins and their annotated locations for XP_009436656.1

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4
      Conserved Domains (3) summary
      cd07212
      Location:480 → 793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285 → 403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]

    19. XM_063807841.1 → XP_063663911.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

    20. XM_063807833.1 → XP_063663903.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    21. XM_063807834.1 → XP_063663904.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    22. XM_024352924.3 → XP_024208692.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9
      Conserved Domains (4) summary
      cd07212
      Location:426 → 739
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:214 → 370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:350 → 395
      Ank_4; Ankyrin repeats (many copies)

    23. XM_009438382.4 → XP_009436657.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      See identical proteins and their annotated locations for XP_009436657.1

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4
      Conserved Domains (3) summary
      cd07212
      Location:480 → 793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285 → 403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]

    24. XM_003317229.6 → XP_003317277.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      See identical proteins and their annotated locations for XP_003317277.1

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9
      Conserved Domains (4) summary
      cd07212
      Location:426 → 739
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:214 → 370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:350 → 395
      Ank_4; Ankyrin repeats (many copies)

    25. XM_003317228.6 → XP_003317276.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      See identical proteins and their annotated locations for XP_003317276.1

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4
      Conserved Domains (3) summary
      cd07212
      Location:480 → 793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285 → 403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]

    26. XM_054675753.2 → XP_054531728.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9

    27. XM_063807826.1 → XP_063663896.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8LNU4, A0A6D2XX29, K6ZYI9

    28. XM_063807821.1 → XP_063663891.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4

    29. XM_054675751.1 → XP_054531726.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4

    30. XM_016939161.4 → XP_016794650.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

      UniProtKB/TrEMBL
      G2HHJ6
      Conserved Domains (4) summary
      cd07212
      Location:302 → 615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107 → 225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108 → 136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12 → 199
      Ank_2; Ankyrin repeats (3 copies)

    31. XM_063807829.1 → XP_063663899.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    32. XM_063807838.1 → XP_063663908.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    33. XM_063807831.1 → XP_063663901.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    34. XM_063807840.1 → XP_063663910.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

    35. XM_063807823.1 → XP_063663893.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      UniProtKB/TrEMBL
      A0A2J8LNV3, A0A6D2Y6C1, H2QLN4

    36. XM_063807832.1 → XP_063663902.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    37. XM_063807835.1 → XP_063663905.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    38. XM_063807843.1 → XP_063663913.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

    39. XM_024352928.3 → XP_024208696.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

      UniProtKB/TrEMBL
      G2HHJ6
      Conserved Domains (4) summary
      cd07212
      Location:302 → 615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107 → 225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108 → 136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12 → 199
      Ank_2; Ankyrin repeats (3 copies)

    RNA

    1. XR_010156020.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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