IREB2 iron responsive element binding protein 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: IREB2provided by VGNC
Official Full Name: iron responsive element binding protein 2provided by VGNC
Primary source: VGNC:VGNC:1935
Locus tag: CK820_G0039830
See related: Ensembl:ENSPTRG00000007342
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	16	NC_072414.2 (70385415..70449204)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	15	NC_072413.1 (70360941..70424069)

Chromosome 16 - NC_072414.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH77805 (e-PCR)
- UniSTS:14877

RH66624 (e-PCR)
- UniSTS:15144

RH44971 (e-PCR)
- UniSTS:1091

IREB2 (e-PCR)
- UniSTS:503115

SHGC-36650 (e-PCR)
- UniSTS:23906

D1S1423 (e-PCR)
- UniSTS:149619

IREB2__6476 (e-PCR)
- UniSTS:463999

SHGC-83059 (e-PCR)
- UniSTS:96150

RH65189 (e-PCR)
- UniSTS:91825

G43287 (e-PCR)
- UniSTS:94921

STS-R99019 (e-PCR)
- UniSTS:70354

A009V40 (e-PCR)
- UniSTS:40921

G32892 (e-PCR)
- UniSTS:117471

SHGC-172971 (e-PCR)
- UniSTS:183523

D15S908 (e-PCR)
- UniSTS:81658

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info	PubMed
enables aconitate hydratase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables iron-responsive element binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in citrate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: iron-responsive element-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

70385415..70449204

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063794250.1 → XP_063650320.1 iron-responsive element-binding protein 2 isoform X1
XM_523125.8 → XP_523125.2 iron-responsive element-binding protein 2 isoform X2

See identical proteins and their annotated locations for XP_523125.2

UniProtKB/TrEMBL

A0A2J8KCJ8, A0A2J8KCK3, A0A6D2WTF4, H2Q9W5

Related

ENSPTRP00000012550.3

Conserved Domains (1) summary

cl28376
Location:10 → 961

AcnA; Aconitase A [Energy production and conversion]
XM_063794251.1 → XP_063650321.1 iron-responsive element-binding protein 2 isoform X1
XM_063794249.1 → XP_063650319.1 iron-responsive element-binding protein 2 isoform X1
XM_063794252.1 → XP_063650322.1 iron-responsive element-binding protein 2 isoform X1