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    PLS3 plastin 3 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 465817, updated on 29-Mar-2024

    Summary

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    Official Symbol
    PLS3provided by VGNC
    Official Full Name
    plastin 3provided by VGNC
    Primary source
    VGNC:VGNC:3832
    Locus tag
    CK820_G0034912
    See related
    Ensembl:ENSPTRG00000022205
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) X NC_072421.2 (113040628..113130163)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) X NC_072421.1 (113036789..113126243)

    Chromosome X - NC_072421.2Genomic Context describing neighboring genes Neighboring gene leucine zipper protein 4 Neighboring gene tubulin alpha-8 chain-like Neighboring gene PHD finger-like domain-containing protein 5A Neighboring gene argininosuccinate synthase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin filament bundle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plastin-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072421.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      113040628..113130163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016943366.4 → XP_016798855.1  plastin-3 isoform X2

      UniProtKB/TrEMBL
      A0A2I3SU43, A0A2J8KYK1, A0A6D2W7M1, K7CKZ3
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21328
      Location:254 → 375
      CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
      cd21331
      Location:377 → 510
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:519 → 630
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

    2. XM_016943364.4 → XP_016798853.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      A0A2I3T4I1, K7CKZ3
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily

    3. XM_016943367.3 → XP_016798856.1  plastin-3 isoform X2

      UniProtKB/TrEMBL
      A0A2I3SU43, A0A2J8KYK1, A0A6D2W7M1, K7CKZ3
      Related
      ENSPTRP00000080497.1
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21328
      Location:254 → 375
      CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
      cd21331
      Location:377 → 510
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:519 → 630
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

    4. XM_016943365.3 → XP_016798854.1  plastin-3 isoform X1

      UniProtKB/TrEMBL
      A0A2I3T4I1, K7CKZ3
      Related
      ENSPTRP00000084134.1
      Conserved Domains (5) summary
      cd00051
      Location:16 → 82
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:101 → 245
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21331
      Location:386 → 519
      CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
      cd21334
      Location:528 → 639
      CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
      cl00030
      Location:254 → 384
      CH_SF; calponin homology (CH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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