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    IL1RAP interleukin 1 receptor accessory protein [ Pan troglodytes (chimpanzee) ]

    Gene ID: 460935, updated on 3-Apr-2024

    Summary

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    Official Symbol
    IL1RAPprovided by VGNC
    Official Full Name
    interleukin 1 receptor accessory proteinprovided by VGNC
    Primary source
    VGNC:VGNC:1847
    Locus tag
    CK820_G0023488
    See related
    Ensembl:ENSPTRG00000015740
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (193654810..193830156)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (193564175..193739528)

    Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene claudin 16 Neighboring gene transmembrane protein 207 Neighboring gene T-complex protein 1 subunit zeta-like Neighboring gene protein enabled homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables interleukin-1 receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables interleukin-1 receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-1 receptor accessory protein
    XP_016797985.1
    XP_016797988.1
    XP_016797990.1
    XP_054537309.1
    XP_054537310.1
    XP_054537311.1
    XP_063663502.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      193654810..193830156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054681334.2 → XP_054537309.1  interleukin-1 receptor accessory protein isoform X1

    2. XM_054681335.2 → XP_054537310.1  interleukin-1 receptor accessory protein isoform X3

    3. XM_054681336.2 → XP_054537311.1  interleukin-1 receptor accessory protein isoform X5

    4. XM_016942499.4 → XP_016797988.1  interleukin-1 receptor accessory protein isoform X4

      Conserved Domains (3) summary
      smart00255
      Location:373 → 516
      TIR; Toll - interleukin 1 - resistance
      smart00410
      Location:222 → 317
      IG_like; Immunoglobulin like
      cl11960
      Location:1 → 100
      Ig; Immunoglobulin domain

    5. XM_016942496.4 → XP_016797985.1  interleukin-1 receptor accessory protein isoform X2

      UniProtKB/TrEMBL
      A0A2I3T322, A0A2J8M684, A0A6D2XQM3
      Conserved Domains (4) summary
      smart00255
      Location:404 → 547
      TIR; Toll - interleukin 1 - resistance
      cd20931
      Location:243 → 349
      Ig3_IL1RAP; Third immunoglobulin domain of interleukin-1 receptor accessory protein (IL1RAP)
      cd20992
      Location:25 → 132
      Ig1_IL1R_like; First immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains
      cd20993
      Location:143 → 235
      Ig2_IL-1RAP_like; Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R), and similar domains

    6. XM_063807432.1 → XP_063663502.1  interleukin-1 receptor accessory protein isoform X6

      UniProtKB/TrEMBL
      A0A2J8M671, A0A6D2WKY5, H2QNY9

    7. XM_016942501.3 → XP_016797990.1  interleukin-1 receptor accessory protein isoform X6

      UniProtKB/TrEMBL
      A0A2J8M671, A0A6D2WKY5, H2QNY9
      Related
      ENSPTRP00000027076.5
      Conserved Domains (3) summary
      pfam01582
      Location:405 → 546
      TIR; TIR domain
      pfam13927
      Location:242 → 335
      Ig_3; Immunoglobulin domain
      cl11960
      Location:26 → 131
      Ig; Immunoglobulin domain

    RNA

    1. XR_008547192.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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