U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PTPN2 protein tyrosine phosphatase non-receptor type 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 455504, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PTPN2provided by VGNC
    Official Full Name
    protein tyrosine phosphatase non-receptor type 2provided by VGNC
    Primary source
    VGNC:VGNC:9915
    Locus tag
    CK820_G0042860
    See related
    Ensembl:ENSPTRG00000009884
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 18
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 17 NC_072415.2 (18020129..18118214)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 18 NC_072416.1 (16943107..17040890)

    Chromosome 17 - NC_072415.2Genomic Context describing neighboring genes Neighboring gene SEH1 like nucleoporin Neighboring gene eukaryotic initiation factor 4A-II-like Neighboring gene uncharacterized LOC104003069 Neighboring gene proteasome assembly chaperone 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-tyrosine dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tyrosine-protein phosphatase non-receptor type 2
    XP_001171536.4
    XP_003953286.4
    XP_009431888.4
    XP_009431889.4
    XP_009431890.4
    XP_009431892.1
    XP_016788746.3
    XP_054527706.1
    XP_054527707.1
    XP_063651985.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072415.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      18020129..18118214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054671731.2 → XP_054527706.1  tyrosine-protein phosphatase non-receptor type 2 isoform X4

    2. XM_001171536.7 → XP_001171536.4  tyrosine-protein phosphatase non-receptor type 2 isoform X5

      UniProtKB/TrEMBL
      K7BD64

    3. XM_009433615.5 → XP_009431890.4  tyrosine-protein phosphatase non-receptor type 2 isoform X2

      UniProtKB/TrEMBL
      K7CXS7

    4. XM_009433613.5 → XP_009431888.4  tyrosine-protein phosphatase non-receptor type 2 isoform X9

    5. XM_009433614.5 → XP_009431889.4  tyrosine-protein phosphatase non-receptor type 2 isoform X1

    6. XM_003953237.5 → XP_003953286.4  tyrosine-protein phosphatase non-receptor type 2 isoform X3

      UniProtKB/TrEMBL
      A0A2I3RTX4

    7. XM_054671732.2 → XP_054527707.1  tyrosine-protein phosphatase non-receptor type 2 isoform X7

    8. XM_009433617.5 → XP_009431892.1  tyrosine-protein phosphatase non-receptor type 2 isoform X6

      UniProtKB/TrEMBL
      A0A2J8JZW7, K7C2Y4
      Conserved Domains (1) summary
      cl28904
      Location:19 → 227
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    9. XM_016933257.4 → XP_016788746.3  tyrosine-protein phosphatase non-receptor type 2 isoform X8

    10. XM_063795915.1 → XP_063651985.1  tyrosine-protein phosphatase non-receptor type 2 isoform X8

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous