APAF1 apoptotic peptidase activating factor 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: APAF1provided by VGNC
Official Full Name: apoptotic peptidase activating factor 1provided by VGNC
Primary source: VGNC:VGNC:4926
Locus tag: CK820_G0016149
See related: Ensembl:ENSPTRG00000005335
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	10	NC_072408.2 (105470699..105560213)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	12	NC_072410.1 (104090513..104177298)

Chromosome 10 - NC_072408.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D11S2921 (e-PCR)
- UniSTS:152074

A009H22 (e-PCR)
- UniSTS:47888

GDB:434012 (e-PCR)
- UniSTS:157204

GDB:313557 (e-PCR)
- UniSTS:8230

RH69665 (e-PCR)
- UniSTS:12332

PMC156606P1 (e-PCR)
- UniSTS:271408

D8S2279 (e-PCR)
- UniSTS:473907

PMC310794P40 (e-PCR)
- UniSTS:272731

G32545 (e-PCR)
- UniSTS:117129

APAF1_7746 (e-PCR)
- UniSTS:466099

SHGC-79800 (e-PCR)
- UniSTS:101101

SHGC-79820 (e-PCR)
- UniSTS:101109

SHGC-79823 (e-PCR)
- UniSTS:101111

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ADP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of apoptosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: apoptotic protease-activating factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

105470699..105560213

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003313880.6 → XP_003313928.4 apoptotic protease-activating factor 1 isoform X1

UniProtKB/TrEMBL

A0A2J8N0G8, A0A8I3B2R9, K7BAU4, K7BEI2
XM_063786991.1 → XP_063643061.1 apoptotic protease-activating factor 1 isoform X3
XM_001151599.7 → XP_001151599.5 apoptotic protease-activating factor 1 isoform X2

UniProtKB/TrEMBL

A0A2J8N0I2, A0A8I3B0J2, K7C2W2
XM_063786992.1 → XP_063643062.1 apoptotic protease-activating factor 1 isoform X4
XM_054663443.2 → XP_054519418.1 apoptotic protease-activating factor 1 isoform X5
XM_063786993.1 → XP_063643063.1 apoptotic protease-activating factor 1 isoform X6
XM_054663444.2 → XP_054519419.1 apoptotic protease-activating factor 1 isoform X7