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    SOCS2 suppressor of cytokine signaling 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 452127, updated on 3-Apr-2024

    Summary

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    Official Symbol
    SOCS2provided by VGNC
    Official Full Name
    suppressor of cytokine signaling 2provided by VGNC
    Primary source
    VGNC:VGNC:5593
    Locus tag
    CK820_G0035568
    See related
    Ensembl:ENSPTRG00000005299
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (100405638..100422009)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (99024970..99041332)

    Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129136674 Neighboring gene mitochondrial ribosomal protein L42 Neighboring gene CASP2 and RIPK1 domain containing adaptor with death domain Neighboring gene uncharacterized LOC107967602

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    suppressor of cytokine signaling 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      100405638..100422009
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016923987.4 → XP_016779476.1  suppressor of cytokine signaling 2 isoform X1

      Conserved Domains (2) summary
      cd10383
      Location:40 → 142
      SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cd03736
      Location:158 → 198
      SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

    2. XM_009425997.4 → XP_009424272.3  suppressor of cytokine signaling 2 isoform X1

    3. XM_016923991.4 → XP_016779480.1  suppressor of cytokine signaling 2 isoform X1

      Conserved Domains (2) summary
      cd10383
      Location:40 → 142
      SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cd03736
      Location:158 → 198
      SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

    4. XM_016923985.4 → XP_016779474.3  suppressor of cytokine signaling 2 isoform X1

    5. XM_016923989.4 → XP_016779478.3  suppressor of cytokine signaling 2 isoform X1

    6. XM_009425998.3 → XP_009424273.3  suppressor of cytokine signaling 2 isoform X2

    7. XM_054664601.2 → XP_054520576.2  suppressor of cytokine signaling 2 isoform X3

    8. XM_063785996.1 → XP_063642066.1  suppressor of cytokine signaling 2 isoform X4

    9. XM_016923986.4 → XP_016779475.1  suppressor of cytokine signaling 2 isoform X1

      Conserved Domains (2) summary
      cd10383
      Location:40 → 142
      SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      cd03736
      Location:158 → 198
      SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

    10. XM_063785997.1 → XP_063642067.1  suppressor of cytokine signaling 2 isoform X5

      UniProtKB/TrEMBL
      A0A2J8KVG7, A0A6D2VVR1, H2Q6L9

    RNA

    1. XR_008538550.2 RNA Sequence

    2. XR_002938851.3 RNA Sequence

    3. XR_010148120.1 RNA Sequence

    4. XR_008538551.2 RNA Sequence

    5. XR_002938849.3 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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