coq5 coenzyme Q5, methyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: coq5provided by ZNC
Official Full Name: coenzyme Q5, methyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040912-5
See related: Ensembl:ENSDARG00000035618 AllianceGenome:ZFIN:ZDB-GENE-040912-5
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92445
Summary: Predicted to enable methyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to act upstream of or within methylation. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 9. Orthologous to human COQ5 (coenzyme Q5, methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (16128214..16139585, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (15627653..15639024, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extrinsic component of mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

Names: DKEYP-7C9.2; coenzyme Q5 homolog, methyltransferase; ubiquinone biosynthesis methyltransferase COQ5, mitochondrial

NP_001004541.1

EC 2.1.1.201

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004541.1 → NP_001004541.1 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial precursor

See identical proteins and their annotated locations for NP_001004541.1

Status: PROVISIONAL

Source sequence(s)

BC078433

UniProtKB/Swiss-Prot

Q66L51

Related

ENSDARP00000051643.4, ENSDART00000051644.5

Conserved Domains (1) summary

PRK00216
Location:56 → 327

ubiE; ubiquinone/menaquinone biosynthesis methyltransferase; Reviewed