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    CDK12 cyclin dependent kinase 12 [ Gallus gallus (chicken) ]

    Gene ID: 428306, updated on 5-Mar-2024

    Summary

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    Symbol
    CDK12provided by CGNC
    Full Name
    cyclin dependent kinase 12provided by CGNC
    Primary source
    CGNC:53328
    See related
    Ensembl:ENSGALG00010026173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CRKRS
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 27
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (4143215..4165667)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (5305942..5328990)

    Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine rich repeat protein 20 Neighboring gene mediator complex subunit 1 Neighboring gene uncharacterized LOC112530403 Neighboring gene neuronal differentiation 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cyclin/CDK positive transcription elongation factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 12
    Names
    Cdc2-related kinase, arginine/serine-rich
    XP_003642852.1
    XP_004948639.1
    XP_004948640.1
    XP_004948641.1
    XP_004948642.1
    XP_040547995.1
    XP_040547996.1
    XP_040547997.1
    XP_040547998.1
    XP_040547999.1
    XP_040548000.1
    XP_425866.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4143215..4165667
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004948582.5 → XP_004948639.1  cyclin-dependent kinase 12 isoform X1

      UniProtKB/TrEMBL
      E1BUG0
      Related
      ENSGALP00010039322.1, ENSGALT00010063732.1
      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    2. XM_004948583.5 → XP_004948640.1  cyclin-dependent kinase 12 isoform X3

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    3. XM_425866.8 → XP_425866.3  cyclin-dependent kinase 12 isoform X2

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    4. XM_003642804.6 → XP_003642852.1  cyclin-dependent kinase 12 isoform X4

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    5. XM_004948584.5 → XP_004948641.1  cyclin-dependent kinase 12 isoform X5

      UniProtKB/TrEMBL
      E1BUG0
      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    6. XM_004948585.5 → XP_004948642.1  cyclin-dependent kinase 12 isoform X6

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5305942..5328990
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040692061.2 → XP_040547995.1  cyclin-dependent kinase 12 isoform X1

      UniProtKB/TrEMBL
      E1BUG0
      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    2. XM_040692063.2 → XP_040547997.1  cyclin-dependent kinase 12 isoform X3

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    3. XM_040692062.2 → XP_040547996.1  cyclin-dependent kinase 12 isoform X2

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    4. XM_040692064.2 → XP_040547998.1  cyclin-dependent kinase 12 isoform X4

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    5. XM_040692065.2 → XP_040547999.1  cyclin-dependent kinase 12 isoform X5

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

    6. XM_040692066.2 → XP_040548000.1  cyclin-dependent kinase 12 isoform X6

      Conserved Domains (1) summary
      cd07864
      Location:719 → 1020
      STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12
    Nucleotide Protein
    Heading Accession and Version

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