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    PLK4 polo like kinase 4 [ Gallus gallus (chicken) ]

    Gene ID: 422497, updated on 5-Mar-2024

    Summary

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    Symbol
    PLK4provided by CGNC
    Full Name
    polo like kinase 4provided by CGNC
    Primary source
    CGNC:51756
    See related
    Ensembl:ENSGALG00010007879
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PLK4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (33918914..33933700)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (33870784..33885625)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112532415 Neighboring gene inturned planar cell polarity protein Neighboring gene heat shock protein family A (Hsp70) member 4 like Neighboring gene uncharacterized LOC121110745 Neighboring gene major facilitator superfamily domain containing 8 Neighboring gene abhydrolase domain containing 18 Neighboring gene uncharacterized LOC121110747 Neighboring gene La ribonucleoprotein domain family member 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase PLK4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      33918914..33933700
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015276633.4 → XP_015132119.2  serine/threonine-protein kinase PLK4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y2C4
      Related
      ENSGALP00010010300.1, ENSGALT00010018750.1
      Conserved Domains (4) summary
      cd13114
      Location:591 → 701
      POLO_box_Plk4_1; First (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13115
      Location:703 → 810
      POLO_box_Plk4_2; Second (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13116
      Location:883 → 961
      POLO_box_Plk4_3; C-terminal (third) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd14186
      Location:10 → 265
      STKc_PLK4; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 4

    2. XM_040699864.2 → XP_040555798.1  serine/threonine-protein kinase PLK4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XQ14, A0A8V0Y2C4
      Related
      ENSGALP00010010299.1, ENSGALT00010018749.1
      Conserved Domains (4) summary
      cd13114
      Location:603 → 713
      POLO_box_Plk4_1; First (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13115
      Location:715 → 822
      POLO_box_Plk4_2; Second (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13116
      Location:895 → 973
      POLO_box_Plk4_3; C-terminal (third) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd14186
      Location:22 → 277
      STKc_PLK4; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 4

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      33870784..33885625
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040671402.2 → XP_040527336.1  serine/threonine-protein kinase PLK4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y2C4
      Conserved Domains (4) summary
      cd13114
      Location:591 → 701
      POLO_box_Plk4_1; First (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13115
      Location:703 → 810
      POLO_box_Plk4_2; Second (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13116
      Location:883 → 961
      POLO_box_Plk4_3; C-terminal (third) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd14186
      Location:10 → 265
      STKc_PLK4; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 4

    2. XM_040671401.2 → XP_040527335.1  serine/threonine-protein kinase PLK4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y2C4
      Conserved Domains (4) summary
      cd13114
      Location:603 → 713
      POLO_box_Plk4_1; First (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13115
      Location:715 → 822
      POLO_box_Plk4_2; Second (cryptic) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd13116
      Location:895 → 973
      POLO_box_Plk4_3; C-terminal (third) polo-box domain (PBD) of polo-like kinase 4 (Plk4/Sak)
      cd14186
      Location:22 → 277
      STKc_PLK4; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 4
    Nucleotide Protein
    Heading Accession and Version

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