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    GCLC glutamate-cysteine ligase catalytic subunit [ Gallus gallus (chicken) ]

    Gene ID: 421894, updated on 5-Mar-2024

    Summary

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    Symbol
    GCLCprovided by CGNC
    Full Name
    glutamate-cysteine ligase catalytic subunitprovided by CGNC
    Primary source
    CGNC:12202
    See related
    Ensembl:ENSGALG00010002041
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See GCLC in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (87865893..87898624)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (87671560..87704258)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110162 Neighboring gene kelch like family member 31 Neighboring gene uncharacterized LOC121110161 Neighboring gene ELOVL fatty acid elongase 5 Neighboring gene glial cells missing homolog 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutamate-cysteine ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of glutamate-cysteine ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate--cysteine ligase catalytic subunit
    XP_040522412.1
    XP_046771224.1
    XP_046795709.1
    XP_419910.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      87865893..87898624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_419910.7 → XP_419910.4  glutamate--cysteine ligase catalytic subunit isoform X1

      UniProtKB/TrEMBL
      F1NQZ9
      Related
      ENSGALP00010002797.1, ENSGALT00010004608.1
      Conserved Domains (1) summary
      pfam03074
      Location:237 → 609
      GCS; Glutamate-cysteine ligase

    2. XM_046939753.1 → XP_046795709.1  glutamate--cysteine ligase catalytic subunit isoform X2

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      87671560..87704258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040666478.2 → XP_040522412.1  glutamate--cysteine ligase catalytic subunit isoform X1

      UniProtKB/TrEMBL
      F1NQZ9
      Conserved Domains (1) summary
      pfam03074
      Location:237 → 609
      GCS; Glutamate-cysteine ligase

    2. XM_046915268.1 → XP_046771224.1  glutamate--cysteine ligase catalytic subunit isoform X2

    Nucleotide Protein
    Heading Accession and Version

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