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    AGTR1 angiotensin II receptor type 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 403836, updated on 5-Mar-2024

    Summary

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    Official Symbol
    AGTR1provided by VGNC
    Official Full Name
    angiotensin II receptor type 1provided by VGNC
    Primary source
    VGNC:VGNC:37720
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    AT1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 23 NC_051827.1 (44190631..44238133)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 23 NC_006605.4 (43434074..43481582)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 23 NC_049244.1 (44086806..44134323)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 23 NC_049283.1 (43779664..43827179)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 23 NC_049764.1 (43832799..43880312)

    Chromosome 23 - NC_051827.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit d, mitochondrial-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC119865416 Neighboring gene carboxypeptidase B1 Neighboring gene carboxypeptidase A3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coronary arteriolar vasoconstriction to angiotensin II is augmented in prediabetic metabolic syndrome via activation of AT1 receptors. Zhang C, et al. Am J Physiol Heart Circ Physiol, 2005 May. PMID 15653764
    2. Molecular cloning of the canine angiotensin II receptor. An AT1-like receptor with reduced affinity for DuP753. Burns L, et al. FEBS Lett, 1994 Apr 25. PMID 8168620
    3. [On angiotensin II receptor distribution after myocardial infarction in dogs]. Qu XF, et al. Zhonghua Xin Xue Guan Bing Za Zhi, 2009 Apr. PMID 19791474
    4. Local stress, not systemic factors, regulate gene expression of the cardiac renin-angiotensin system in vivo: a comprehensive study of all its components in the dog. Lee YA, et al. Proc Natl Acad Sci U S A, 1996 Oct 1. PMID 8855304, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables angiotensin type II receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type-1 angiotensin II receptor
    Names
    Angiotensin II type-1 receptor
    Type-1 angiotensin II receptor
    angiotensin II type 1 receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051827.1 Reference ROS_Cfam_1.0

      Range
      44190631..44238133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038432622.1 → XP_038288550.1  type-1 angiotensin II receptor

      UniProtKB/Swiss-Prot
      P43240
      UniProtKB/TrEMBL
      A0A8C0L3S2
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038432621.1 → XP_038288549.1  type-1 angiotensin II receptor

      UniProtKB/Swiss-Prot
      P43240
      UniProtKB/TrEMBL
      A0A8C0L3S2
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049283.1 Alternate UMICH_Zoey_3.1

      Range
      43779664..43827179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038507918.1 → XP_038363846.1  type-1 angiotensin II receptor

      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038507917.1 → XP_038363845.1  type-1 angiotensin II receptor

      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049764.1 Alternate UNSW_CanFamBas_1.0

      Range
      43832799..43880312
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038635352.1 → XP_038491280.1  type-1 angiotensin II receptor

      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038635351.1 → XP_038491279.1  type-1 angiotensin II receptor

      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049244.1 Alternate UU_Cfam_GSD_1.0

      Range
      44086806..44134323
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038571160.1 → XP_038427088.1  type-1 angiotensin II receptor

      UniProtKB/Swiss-Prot
      P43240
      UniProtKB/TrEMBL
      A0A8C0L3S2
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_038571159.1 → XP_038427087.1  type-1 angiotensin II receptor

      UniProtKB/Swiss-Prot
      P43240
      UniProtKB/TrEMBL
      A0A8C0L3S2
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      43434074..43481582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005634552.4 → XP_005634609.1  type-1 angiotensin II receptor

      See identical proteins and their annotated locations for XP_005634609.1

      UniProtKB/Swiss-Prot
      P43240
      UniProtKB/TrEMBL
      A0A8C0L3S2
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_003433161.5 → XP_003433209.1  type-1 angiotensin II receptor

      See identical proteins and their annotated locations for XP_003433209.1

      UniProtKB/Swiss-Prot
      P43240
      UniProtKB/TrEMBL
      A0A8C0L3S2
      Conserved Domains (1) summary
      cd15192
      Location:29 → 313
      7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43240.1 GenPept UniProtKB/Swiss-Prot:P43240

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