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    ITGA2B integrin subunit alpha 2b [ Canis lupus familiaris (dog) ]

    Gene ID: 403789, updated on 5-Mar-2024

    Summary

    Official Symbol
    ITGA2Bprovided by VGNC
    Official Full Name
    integrin subunit alpha 2bprovided by VGNC
    Primary source
    VGNC:VGNC:42124
    See related
    Ensembl:ENSCAFG00845007943
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    GPIIB
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 9
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (19744435..19758300)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (18439814..18453677)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (18925492..18939347)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (18598247..18612116)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (18781219..18795078)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111097345 Neighboring gene G-patch domain containing 8 Neighboring gene family with sequence similarity 171 member A2 Neighboring gene granulin precursor

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    integrin alpha-IIb
    Names
    glycoprotein GPIIb
    integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003163.2NP_001003163.1  integrin alpha-IIb

      See identical proteins and their annotated locations for NP_001003163.1

      Status: PROVISIONAL

      Source sequence(s)
      AF170524
      UniProtKB/TrEMBL
      A0A8C0KC46, A0A8P0NG23, Q9TUN8
      Related
      ENSCAFP00845010846.1, ENSCAFT00845013996.1
      Conserved Domains (2) summary
      smart00191
      Location:384438
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:481920
      Integrin_alpha2; Integrin alpha

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      19744435..19758300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      18598247..18612116
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      18781219..18795078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      18925492..18939347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      18439814..18453677
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)