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    DES desmin [ Gallus gallus (chicken) ]

    Gene ID: 395906, updated on 5-Mar-2024

    Summary

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    Official Symbol
    DESprovided by CGNC
    Official Full Name
    desminprovided by CGNC
    Primary source
    CGNC:49543
    See related
    Ensembl:ENSGALG00010018306
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (21794233..21798343, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (21713552..21717663, complement)

    Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene GDP-mannose pyrophosphorylase A Neighboring gene SPEG complex locus Neighboring gene aspartyl aminopeptidase Neighboring gene protein tyrosine phosphatase, receptor type N

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Localization of the actin-binding protein fesselin in chicken smooth muscle. Renegar RH, et al. Histochem Cell Biol, 2009 Feb. PMID 18820943, Free PMC Article
    2. Characterization and regulation in the expression of a gene coding for the intermediate filament protein desmin. Capetanaki YG, et al. Proc Natl Acad Sci U S A, 1984 Nov. PMID 6594672, Free PMC Article
    3. Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis. Kurz H, et al. Histochem Cell Biol, 2008 Nov. PMID 18688635
    4. Actin isoform compartments in chicken gizzard smooth muscle cells. North AJ, et al. J Cell Sci, 1994 Mar. PMID 8006065
    5. Specific recognition of coiled coils by infrared spectroscopy: analysis of the three structural domains of type III intermediate filament proteins. Heimburg T, et al. Biochemistry, 1996 Feb 6. PMID 8634266

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In skeletal muscle, fesselin was associated with desmin in regularly spaced bands distributed along the length of muscle fibers suggesting localization to the Z-line.
      Title: Localization of the actin-binding protein fesselin in chicken smooth muscle.
    2. Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis.
      Title: Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in skeletal muscle organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in sarcolemma IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    desmin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396679.1 → NP_001383608.1  desmin

      Status: VALIDATED

      Source sequence(s)
      AB011672, BM427242, BM439452, CD218673, CN233024, K02445
      UniProtKB/Swiss-Prot
      E1BZ05, P02542
      UniProtKB/TrEMBL
      O73665
      Related
      ENSGALP00010026265.1, ENSGALT00010044167.1
      Conserved Domains (2) summary
      pfam00038
      Location:99 → 407
      Filament; Intermediate filament protein
      pfam04732
      Location:17 → 98
      Filament_head; Intermediate filament head (DNA binding) region

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      21794233..21798343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      21713552..21717663 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P02542.2 GenPept UniProtKB/Swiss-Prot:P02542

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.