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    Gask1a golgi associated kinase 1A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316090, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Gask1aprovided by RGD
    Official Full Name
    golgi associated kinase 1Aprovided by RGD
    Primary source
    RGD:1305157
    See related
    Ensembl:ENSRNOG00000025676 AllianceGenome:RGD:1305157
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam198a; RGD1305157
    Summary
    Predicted to be located in endoplasmic reticulum and extracellular region. Predicted to be active in Golgi apparatus. Orthologous to human GASK1A (golgi associated kinase 1A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 34.1), Thymus (RPKM 18.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gask1a in Genome Data Viewer
    Location:
    8q32
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (130488279..130521242)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (121610779..121643742)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130581072..130614118)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 8 subfamily B member 1 Neighboring gene poly(rC) binding protein 2 like 1 Neighboring gene KRAB box domain containing 1 Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) Neighboring gene uncharacterized LOC134480254 Neighboring gene uncharacterized LOC134480253

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Fam198a, a member of secreted kinase, secrets through caveolae biogenesis pathway. Wei Z, et al. Acta Biochim Biophys Sin (Shanghai), 2018 Oct 1. PMID 30188967
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Golgi-associated kinase 1A
    Names
    family with sequence similarity 198, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399327.1 → NP_001386256.1  Golgi-associated kinase 1A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      F1M9D8
      Related
      ENSRNOP00000014323.6, ENSRNOT00000014323.8
      Conserved Domains (1) summary
      pfam15051
      Location:238 → 562
      FAM198; FAM198 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      130488279..130521242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265662.1 → XP_063121732.1  Golgi-associated kinase 1A isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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