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    Ranbp6 RAN binding protein 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309326, updated on 5-Mar-2024

    Summary

    Official Symbol
    Ranbp6provided by RGD
    Official Full Name
    RAN binding protein 6provided by RGD
    Primary source
    RGD:1305165
    See related
    Ensembl:ENSRNOG00000053859 AllianceGenome:RGD:1305165
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to be active in cytoplasm and nucleus. Orthologous to human RANBP6 (RAN binding protein 6). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    1q52
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (236985930..236990451, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (227572394..227576915, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (247980976..247985553, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene melan-A Neighboring gene bromodomain containing 10 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene tRNA methyltransferase 6, pseudogene 1 Neighboring gene interleukin 33 Neighboring gene uncharacterized LOC134485220

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107584.1NP_001101054.1  ran-binding protein 6

      See identical proteins and their annotated locations for NP_001101054.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473953
      UniProtKB/TrEMBL
      A6I0X4, D4A634
      Related
      ENSRNOP00000074790.2, ENSRNOT00000078998.2
      Conserved Domains (5) summary
      COG5215
      Location:309640
      KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
      sd00044
      Location:330353
      HEAT; HEAT repeat [structural motif]
      pfam18808
      Location:284365
      Importin_rep_4; Importin repeat
      pfam18816
      Location:10131060
      Importin_rep_5; Importin repeat
      pfam18829
      Location:773882
      Importin_rep_6; Importin repeat 6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      236985930..236990451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264595.1XP_063120665.1  ran-binding protein 6 isoform X1