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    Klhl35 kelch-like family member 35 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308850, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Klhl35provided by RGD
    Official Full Name
    kelch-like family member 35provided by RGD
    Primary source
    RGD:1565895
    See related
    Ensembl:ENSRNOG00000017365 AllianceGenome:RGD:1565895
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565895
    Summary
    Orthologous to human KLHL35 (kelch like family member 35). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 8.5), Brain (RPKM 5.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    1q32
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (163172811..163185663)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (153767138..153773550)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (164419052..164431055)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483761 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 5 Neighboring gene uncharacterized LOC134483762 Neighboring gene small nucleolar RNA, C/D box 15B Neighboring gene small nucleolar RNA, C/D box 15A Neighboring gene ribosomal protein S3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    kelch-like protein 35
    Names
    kelch-like 35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      163172811..163185663
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_218953.8 → XP_218953.4  kelch-like protein 35 isoform X1

      UniProtKB/TrEMBL
      D4A6V5
      Related
      ENSRNOP00000023386.4
      Conserved Domains (6) summary
      smart00612
      Location:396 → 442
      Kelch; Kelch domain
      smart00225
      Location:51 → 151
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:341 → 381
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:40 → 147
      BTB; BTB/POZ domain
      pfam01344
      Location:340 → 381
      Kelch_1; Kelch motif
      pfam07707
      Location:173 → 258
      BACK; BTB And C-terminal Kelch

    2. XM_039101100.2 → XP_038957028.1  kelch-like protein 35 isoform X2

      UniProtKB/TrEMBL
      D4A6V5
    Nucleotide Protein Strain
    Heading Accession and Version

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