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    arc4 ARP2/3 actin-organizing complex subunit Arc4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541767, updated on 15-Mar-2024

    Summary

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    Gene symbol
    arc4
    Gene description
    ARP2/3 actin-organizing complex subunit Arc4
    Primary source
    PomBase:SPAC6G9.07c
    Locus tag
    SPAC6G9.07c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (3258471..3259527, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative coenzyme A diphosphatase Neighboring gene miscRNA Neighboring gene pericentrin Pcp1 Neighboring gene ubiquitin hydrolase Ubp6 Neighboring gene 60S ribosomal protein L24 Neighboring gene helicase Sen1 Neighboring gene synaptobrevin family receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe Arc3 is a conserved subunit of the Arp2/3 complex required for polarity, actin organization, and endocytosis. Cabrera R, et al. Yeast, 2011 Jun. PMID 21449051, Free PMC Article
    2. A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast. Morrell JL, et al. Mol Biol Cell, 1999 Dec. PMID 10588653, Free PMC Article
    3. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. Nolen BJ, et al. J Biol Chem, 2008 Sep 26. PMID 18640983, Free PMC Article
    4. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. Skau CT, et al. J Biol Chem, 2011 Jul 29. PMID 21642440, Free PMC Article
    5. Pathway of actin filament branch formation by Arp2/3 complex. Beltzner CC, et al. J Biol Chem, 2008 Mar 14. PMID 18165685

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Arp2/3 complex-mediated actin nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Arp2/3 complex-mediated actin nucleation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin cortical patch assembly IC
    Inferred by Curator
    more info
    		  
    involved_in endocytosis IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Arp2/3 protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in actin cortical patch IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ARP2/3 actin-organizing complex subunit Arc4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3258471..3259527 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019540.2 → NP_594116.1  ARP2/3 actin-organizing complex subunit Arc4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594116.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q92352, Q9URL0
      Conserved Domains (1) summary
      pfam05856
      Location:1 → 166
      ARPC4; ARP2/3 complex 20 kDa subunit (ARPC4)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    3DWL_F.1
    3DWL_K.1

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