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    prp17 splicing factor Prp17 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541168, updated on 7-Apr-2024

    Summary

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    Gene symbol
    prp17
    Gene description
    splicing factor Prp17
    Primary source
    PomBase:SPBC6B1.10
    Locus tag
    SPBC6B1.10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003423.3 (2651044..2659395)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene U4/U6 x U5 tri-snRNP complex subunit Prp1 Neighboring gene 2-oxoglutarate and Fe(2+) dioxygenase domain-containing protein 1 Neighboring gene SAGA complex subunit Sus1 Neighboring gene Mre11 complex subunit Nbs1 Neighboring gene 1-phosphatidylinositol-3-phosphate 5-kinase Fab1 Neighboring gene miscRNA Neighboring gene heat shock protein Hsp16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression. Saha D, et al. Biochem Biophys Res Commun, 2012 Aug 3. PMID 22789856
    2. Structure of a yeast spliceosome at 3.6-angstrom resolution. Yan C, et al. Science, 2015 Sep 11. PMID 26292707
    3. The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast. Aronica L, et al. Nucleic Acids Res, 2016 Feb 29. PMID 26682798, Free PMC Article
    4. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article
    5. Identification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe. Cipakova I, et al. Cell Cycle, 2019 Jul. PMID 31219728, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. genetic interactions between BUD31 and PRP17 were examined.
      Title: Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Prp19 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing factor Prp17

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2651044..2659395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001355781.1 → NP_001342709.1  splicing factor Prp17 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43071
      Conserved Domains (2) summary
      cd00200
      Location:258 → 558
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:269 → 308
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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