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    aatf-1 Protein BFR2 [ Caenorhabditis elegans ]

    Gene ID: 171723, updated on 23-Nov-2023

    Summary

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    Gene symbol
    aatf-1
    Gene description
    Protein BFR2
    Primary source
    WormBase:WBGene00022269
    Locus tag
    CELE_Y73E7A.2
    See related
    AllianceGenome:WB:WBGene00022269
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human AATF (apoptosis antagonizing transcription factor). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (1601838..1607219)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Putative complexin-1 Neighboring gene pseudo Neighboring gene Bladder cancer-associated protein Neighboring gene WD and tetratricopeptide repeats protein 1;WD_REPEATS_REGION domain-containing protein Neighboring gene Beta-1,4-N-acetylgalactosaminyltransferase bre-4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein BFR2
    NP_490870.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1601838..1607219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058469.8 → NP_490870.2  Protein BFR2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490870.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GUM5
      Conserved Domains (2) summary
      pfam08164
      Location:375 → 462
      TRAUB; Apoptosis-antagonizing transcription factor, C-terminal
      pfam13339
      Location:142 → 303
      AATF-Che1; Apoptosis antagonizing transcription factor
    Nucleotide Protein
    Heading Accession and Version

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