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    INF2 inverted formin 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 102153864, updated on 10-Mar-2024

    Summary

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    Gene symbol
    INF2
    Gene description
    inverted formin 2
    See related
    Ensembl:ENSCAFG00845021549
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (72543585..72560033)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (71774391..71791628)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (72659616..72686357)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (72226504..72231172) , (72231643..72242771)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (72269581..72286805)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 179 Neighboring gene uncharacterized LOC119873034 Neighboring gene uncharacterized LOC119873033 Neighboring gene adenylosuccinate synthase 1 Neighboring gene SIVA1 apoptosis inducing factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assembly of the β4-Integrin Interactome Based on Proximal Biotinylation in the Presence and Absence of Heterodimerization. Myllymäki SM, et al. Mol Cell Proteomics, 2019 Feb. PMID 30404858, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: inverted formin-2; inverted formin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      72543585..72560033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038674813.1 → XP_038530741.1  LOW QUALITY PROTEIN: inverted formin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MC85
      Related
      ENSCAFT00845038037.1
      Conserved Domains (5) summary
      PHA03307
      Location:1002 → 1257
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam06367
      Location:188 → 373
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:46 → 184
      Drf_GBD; Diaphanous GTPase-binding Domain
      cd22061
      Location:974 → 1003
      WH2_INF2; Wiskott Aldrich syndrome homology region 2 (WH2 motif) found in Inverted formin-2 (INF2)
      cl19758
      Location:564 → 928
      FH2; Formin Homology 2 Domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      72226504..72231172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    2. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      72231643..72242771
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038484373.1 → XP_038340301.1  inverted formin-2 isoform X2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      72269581..72286805
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038609971.1 → XP_038465899.1  LOW QUALITY PROTEIN: inverted formin-2 isoform X4

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      72659616..72686357
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038545909.1 → XP_038401837.1  inverted formin-2 isoform X7

      UniProtKB/TrEMBL
      A0A8C0K5F9

    2. XM_038545908.1 → XP_038401836.1  inverted formin-2 isoform X7

      UniProtKB/TrEMBL
      A0A8C0K5F9

    3. XM_038545907.1 → XP_038401835.1  inverted formin-2 isoform X6

      UniProtKB/TrEMBL
      A0A8C0MC85

    4. XM_038545906.1 → XP_038401834.1  inverted formin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0MC85

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      71774391..71791628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038596891.1 → XP_038452819.1  LOW QUALITY PROTEIN: inverted formin-2 isoform X8

      UniProtKB/TrEMBL
      A0A8C0MC85
      Conserved Domains (5) summary
      PRK07764
      Location:997 → 1169
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      pfam06367
      Location:188 → 373
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:46 → 184
      Drf_GBD; Diaphanous GTPase-binding Domain
      cd22061
      Location:974 → 1003
      WH2_INF2; Wiskott Aldrich syndrome homology region 2 (WH2 motif) found in Inverted formin-2 (INF2)
      cl19758
      Location:564 → 928
      FH2; Formin Homology 2 Domain
    Nucleotide Protein
    Heading Accession and Version

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