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    ZNF517 zinc finger protein 517 [ Canis lupus familiaris (dog) ]

    Gene ID: 102153851, updated on 10-Mar-2024

    Summary

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    Official Symbol
    ZNF517provided by VGNC
    Official Full Name
    zinc finger protein 517provided by VGNC
    Primary source
    VGNC:VGNC:48747
    See related
    Ensembl:ENSCAFG00845012057
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human all
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    Genomic context

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    Location:
    chromosome: 13
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (38561749..38575476, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (38048731..38062439, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (38838546..38851137, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (38253484..38266974, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (38362150..38375830, complement)

    Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 7 Neighboring gene uncharacterized LOC119864296 Neighboring gene ribosomal protein L8 Neighboring gene zinc finger protein 34 Neighboring gene zinc finger protein 250

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: zinc finger protein 517; zinc finger protein 517

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051817.1 Reference ROS_Cfam_1.0

      Range
      38561749..38575476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038685421.1 → XP_038541349.1  zinc finger protein 517 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:102 → 161
      KRAB; krueppel associated box
      COG5048
      Location:271 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_038685427.1 → XP_038541355.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_038685423.1 → XP_038541351.1  zinc finger protein 517 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:183 → 462
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_038685426.1 → XP_038541354.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_038685422.1 → XP_038541350.1  zinc finger protein 517 isoform X2

      Related
      ENSCAFP00845016853.1, ENSCAFT00845021444.1
      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:183 → 462
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_038685425.1 → XP_038541353.1  zinc finger protein 517 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8Q3, A0A8C0TI56, A0A8I3RZ40
      Related
      ENSCAFP00845016834.1, ENSCAFT00845021419.1
      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    7. XM_038685424.1 → XP_038541352.1  zinc finger protein 517 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8Q3, A0A8C0TI56, A0A8I3RZ40
      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    8. XM_038685428.1 → XP_038541356.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049273.1 Alternate UMICH_Zoey_3.1

      Range
      38253484..38266974 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038493579.1 → XP_038349507.1  zinc finger protein 517 isoform X1

    2. XM_038493585.1 → XP_038349513.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_038493581.1 → XP_038349509.1  zinc finger protein 517 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:183 → 462
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_038493584.1 → XP_038349512.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_038493580.1 → XP_038349508.1  zinc finger protein 517 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:183 → 462
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_038493583.1 → XP_038349511.1  zinc finger protein 517 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    7. XM_038493582.1 → XP_038349510.1  zinc finger protein 517 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    8. XM_038493586.1 → XP_038349514.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

      Range
      38362150..38375830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038619811.1 → XP_038475739.1  zinc finger protein 517 isoform X1

    2. XM_038619816.1 → XP_038475744.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_038619812.1 → XP_038475740.1  zinc finger protein 517 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:183 → 462
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_038619815.1 → XP_038475743.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_038619814.1 → XP_038475742.1  zinc finger protein 517 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    6. XM_038619813.1 → XP_038475741.1  zinc finger protein 517 isoform X3

      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    7. XM_038619817.1 → XP_038475745.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

      Range
      38838546..38851137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038555918.1 → XP_038411846.1  LOW QUALITY PROTEIN: zinc finger protein 517 isoform X5

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      38048731..38062439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022426896.2 → XP_022282604.1  zinc finger protein 517 isoform X1

      Conserved Domains (3) summary
      smart00349
      Location:102 → 161
      KRAB; krueppel associated box
      COG5048
      Location:271 → 550
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_038689377.1 → XP_038545305.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_005628115.4 → XP_005628172.1  zinc finger protein 517 isoform X2

      UniProtKB/TrEMBL
      J9NVQ6
      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:183 → 462
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_038689368.1 → XP_038545296.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_038689343.1 → XP_038545271.1  zinc finger protein 517 isoform X2

      Conserved Domains (3) summary
      smart00349
      Location:14 → 73
      KRAB; krueppel associated box
      COG5048
      Location:183 → 462
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_038689360.1 → XP_038545288.1  zinc finger protein 517 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8Q3, A0A8C0TI56, A0A8I3RZ40
      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    7. XM_038689356.1 → XP_038545284.1  zinc finger protein 517 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8Q3, A0A8C0TI56, A0A8I3RZ40
      Conserved Domains (3) summary
      COG5048
      Location:141 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:168 → 188
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 31
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    8. XM_038689385.1 → XP_038545313.1  zinc finger protein 517 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:89 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:116 → 136
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
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