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    SMG6 SMG6 nonsense mediated mRNA decay factor [ Gallus gallus (chicken) ]

    Gene ID: 101750600, updated on 8-Mar-2024

    Summary

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    Official Symbol
    SMG6provided by CGNC
    Official Full Name
    SMG6 nonsense mediated mRNA decay factorprovided by CGNC
    Primary source
    CGNC:70047
    See related
    Ensembl:ENSGALG00010029402
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See SMG6 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (6011406..6102369, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (5747920..5838873, complement)

    Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-132c Neighboring gene microRNA mir-212 Neighboring gene HIC ZBTB transcriptional repressor 1 Neighboring gene uncharacterized LOC107054801 Neighboring gene uncharacterized LOC107054800 Neighboring gene microRNA 1666 Neighboring gene microRNA 1696 Neighboring gene small nucleolar RNA SNORD91 family Neighboring gene serine racemase Neighboring gene TSR1 ribosome maturation factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomerase RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of telomerase holoenzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    telomerase-binding protein EST1A
    Names
    Smg-6 homolog, nonsense mediated mRNA decay factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      6011406..6102369 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004946548.5 → XP_004946605.3  telomerase-binding protein EST1A isoform X4

      UniProtKB/TrEMBL
      A0A8V1AM23
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1246 → 1421
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    2. XM_004946547.5 → XP_004946604.3  telomerase-binding protein EST1A isoform X3

      UniProtKB/TrEMBL
      A0A8V1AI38, A0A8V1AM23
      Related
      ENSGALP00010043810.1, ENSGALT00010071119.1
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1247 → 1422
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    3. XM_040650407.2 → XP_040506341.1  telomerase-binding protein EST1A isoform X2

      UniProtKB/TrEMBL
      A0A8V1AM23
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1281 → 1456
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    4. XM_040650405.2 → XP_040506339.1  telomerase-binding protein EST1A isoform X1

      UniProtKB/TrEMBL
      A0A8V1AM23
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1282 → 1457
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    5. XM_040650408.2 → XP_040506342.1  telomerase-binding protein EST1A isoform X5

      Conserved Domains (1) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5747920..5838873 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040687209.2 → XP_040543143.1  telomerase-binding protein EST1A isoform X4

      UniProtKB/TrEMBL
      A0A8V1AM23
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1246 → 1421
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    2. XM_040687208.2 → XP_040543142.1  telomerase-binding protein EST1A isoform X3

      UniProtKB/TrEMBL
      A0A8V1AI38, A0A8V1AM23
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1247 → 1422
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    3. XM_040687207.2 → XP_040543141.1  telomerase-binding protein EST1A isoform X2

      UniProtKB/TrEMBL
      A0A8V1AM23
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1281 → 1456
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    4. XM_040687206.2 → XP_040543140.1  telomerase-binding protein EST1A isoform X1

      UniProtKB/TrEMBL
      A0A8V1AM23
      Conserved Domains (2) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
      cd09885
      Location:1282 → 1457
      PIN_Smg6-like; VapC-like PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs

    5. XM_040687210.2 → XP_040543144.1  telomerase-binding protein EST1A isoform X5

      Conserved Domains (1) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]

    6. XM_040687211.2 → XP_040543145.1  telomerase-binding protein EST1A isoform X5

      Conserved Domains (1) summary
      sd00006
      Location:770 → 800
      TPR; TPR repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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