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    SIGIRR single Ig and TIR domain containing [ Canis lupus familiaris (dog) ]

    Gene ID: 100686933, updated on 8-Mar-2024

    Summary

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    Official Symbol
    SIGIRRprovided by VGNC
    Official Full Name
    single Ig and TIR domain containingprovided by VGNC
    Primary source
    VGNC:VGNC:46167
    See related
    Ensembl:ENSCAFG00845029342
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (26132543..26138716, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (25197564..25203757, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (25899941..25906134, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (25642654..25648846, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (25287402..25293596, complement)

    Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene beta-1,4-N-acetyl-galactosaminyltransferase 4 Neighboring gene plakophilin 3 Neighboring gene anoctamin 9 Neighboring gene nascent polypeptide-associated complex subunit alpha, muscle-specific form-like Neighboring gene uncharacterized LOC111090923

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    single Ig IL-1-related receptor
    Names
    single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051822.1 Reference ROS_Cfam_1.0

      Range
      26132543..26138716 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038423989.1 → XP_038279917.1  single Ig IL-1-related receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:169 → 315
      TIR; TIR domain
      cd00096
      Location:17 → 20
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:9 → 102
      Ig; Immunoglobulin domain

    2. XM_038423990.1 → XP_038279918.1  single Ig IL-1-related receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Related
      ENSCAFP00845040761.1, ENSCAFT00845051952.1
      Conserved Domains (3) summary
      pfam01582
      Location:166 → 312
      TIR; TIR domain
      cd00096
      Location:29 → 33
      Ig; Ig strand B [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    3. XM_038423988.1 → XP_038279916.1  single Ig IL-1-related receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:170 → 316
      TIR; TIR domain
      cd00096
      Location:18 → 21
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049278.1 Alternate UMICH_Zoey_3.1

      Range
      25642654..25648846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038500347.1 → XP_038356275.1  single Ig IL-1-related receptor isoform X2

      Conserved Domains (3) summary
      pfam01582
      Location:169 → 315
      TIR; TIR domain
      cd00096
      Location:17 → 20
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:9 → 102
      Ig; Immunoglobulin domain

    2. XM_038500348.1 → XP_038356276.1  single Ig IL-1-related receptor isoform X3

      Conserved Domains (3) summary
      pfam01582
      Location:166 → 312
      TIR; TIR domain
      cd00096
      Location:29 → 33
      Ig; Ig strand B [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    3. XM_038500346.1 → XP_038356274.1  single Ig IL-1-related receptor isoform X1

      Conserved Domains (3) summary
      pfam01582
      Location:170 → 316
      TIR; TIR domain
      cd00096
      Location:18 → 21
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

      Range
      25287402..25293596 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038627031.1 → XP_038482959.1  single Ig IL-1-related receptor isoform X2

      Conserved Domains (3) summary
      pfam01582
      Location:169 → 315
      TIR; TIR domain
      cd00096
      Location:17 → 20
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:9 → 102
      Ig; Immunoglobulin domain

    2. XM_038627032.1 → XP_038482960.1  single Ig IL-1-related receptor isoform X3

      Conserved Domains (3) summary
      pfam01582
      Location:166 → 312
      TIR; TIR domain
      cd00096
      Location:29 → 33
      Ig; Ig strand B [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    3. XM_038627030.1 → XP_038482958.1  single Ig IL-1-related receptor isoform X1

      Conserved Domains (3) summary
      pfam01582
      Location:170 → 316
      TIR; TIR domain
      cd00096
      Location:18 → 21
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

      Range
      25899941..25906134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038562910.1 → XP_038418838.1  single Ig IL-1-related receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:169 → 315
      TIR; TIR domain
      cd00096
      Location:17 → 20
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:9 → 102
      Ig; Immunoglobulin domain

    2. XM_038562911.1 → XP_038418839.1  single Ig IL-1-related receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:166 → 312
      TIR; TIR domain
      cd00096
      Location:29 → 33
      Ig; Ig strand B [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    3. XM_038562909.1 → XP_038418837.1  single Ig IL-1-related receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:170 → 316
      TIR; TIR domain
      cd00096
      Location:18 → 21
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      25197564..25203757 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038454202.1 → XP_038310130.1  single Ig IL-1-related receptor isoform X2

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:169 → 315
      TIR; TIR domain
      cd00096
      Location:17 → 20
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:9 → 102
      Ig; Immunoglobulin domain

    2. XM_038454203.1 → XP_038310131.1  single Ig IL-1-related receptor isoform X3

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:166 → 312
      TIR; TIR domain
      cd00096
      Location:29 → 33
      Ig; Ig strand B [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain

    3. XM_038454201.1 → XP_038310129.1  single Ig IL-1-related receptor isoform X1

      UniProtKB/TrEMBL
      A0A8C0K2Z7, A0A8C0TJ13, A0A8I3SC96
      Conserved Domains (3) summary
      pfam01582
      Location:170 → 316
      TIR; TIR domain
      cd00096
      Location:18 → 21
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:10 → 103
      Ig; Immunoglobulin domain
    Nucleotide Protein
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