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    ptprn2 protein tyrosine phosphatase receptor type N2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100495746, updated on 8-Mar-2024

    Summary

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    Official Symbol
    ptprn2provided by Xenbase
    Official Full Name
    protein tyrosine phosphatase receptor type N2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-12565070
    See related
    Ensembl:ENSXETG00000043361
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    iar; icaar; ptprp; phogrin; ia-2beta; r-ptp-n2
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (17833315..18453930, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (10051412..10646350, complement)

    Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105947595 Neighboring gene DnaJ heat shock protein family (Hsp40) member B6 Neighboring gene microRNA mir-153-2 Neighboring gene non-SMC condensin II complex subunit G2 Neighboring gene extended synaptotagmin-like protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in secretory granule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in transport vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    receptor-type tyrosine-protein phosphatase N2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      17833315..18453930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002935174.5 → XP_002935220.2  receptor-type tyrosine-protein phosphatase N2

      UniProtKB/TrEMBL
      A0A803JMP5
      Related
      ENSXETP00000110998.1, ENSXETT00000122727.1
      Conserved Domains (4) summary
      smart00194
      Location:779 → 1038
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:807 → 1038
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam11548
      Location:546 → 631
      Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
      pfam14948
      Location:62 → 120
      RESP18; RESP18 domain
    Nucleotide Protein Strain
    Heading Accession and Version

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