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    fgd3 FYVE, RhoGEF and PH domain containing 3 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100490625, updated on 8-Mar-2024

    Summary

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    Official Symbol
    fgd3provided by Xenbase
    Official Full Name
    FYVE, RhoGEF and PH domain containing 3provided by Xenbase
    Primary source
    Xenbase:XB-GENE-995891
    See related
    Ensembl:ENSXETG00000034175
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    zfyve5
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (150903024..150981882)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683495.1 (165174..238249, complement)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 40 Neighboring gene bicaudal D homolog 2 Neighboring gene sushi domain containing 3 Neighboring gene caspase recruitment domain family member 19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    FYVE, RhoGEF and PH domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      150903024..150981882
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004914180.4 → XP_004914237.2  FYVE, RhoGEF and PH domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A6I8QX31, A0A8J0R3D3
      Related
      ENSXETP00000058649.3, ENSXETT00000062056.3
      Conserved Domains (4) summary
      cd13236
      Location:778 → 882
      PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
      cd13387
      Location:538 → 645
      PH1_FGD3; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 3, N-terminal Pleckstrin homology (PH) domain
      cd15740
      Location:696 → 751
      FYVE_FGD3; FYVE-like domain found in FYVE, RhoGEF and PH domain-containing protein 3 (FGD3) and similar proteins
      pfam00621
      Location:328 → 506
      RhoGEF; RhoGEF domain

    2. XM_012961791.3 → XP_012817245.2  FYVE, RhoGEF and PH domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1B8Y3W3, A0A6I8S184
      Related
      ENSXETP00000090675.2, ENSXETT00000104464.2
      Conserved Domains (4) summary
      cd13236
      Location:637 → 741
      PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
      cd13387
      Location:397 → 504
      PH1_FGD3; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 3, N-terminal Pleckstrin homology (PH) domain
      cd15740
      Location:555 → 610
      FYVE_FGD3; FYVE-like domain found in FYVE, RhoGEF and PH domain-containing protein 3 (FGD3) and similar proteins
      pfam00621
      Location:187 → 365
      RhoGEF; RhoGEF domain

    3. XM_002941737.5 → XP_002941783.3  FYVE, RhoGEF and PH domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A1B8Y3W3, A0A6I8S184
      Conserved Domains (4) summary
      cd13236
      Location:637 → 741
      PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
      cd13387
      Location:397 → 504
      PH1_FGD3; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 3, N-terminal Pleckstrin homology (PH) domain
      cd15740
      Location:555 → 610
      FYVE_FGD3; FYVE-like domain found in FYVE, RhoGEF and PH domain-containing protein 3 (FGD3) and similar proteins
      pfam00621
      Location:187 → 365
      RhoGEF; RhoGEF domain
    Nucleotide Protein Strain
    Heading Accession and Version

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