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    itih6 inter-alpha-trypsin inhibitor heavy chain family member 6 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100488634, updated on 8-Mar-2024

    Summary

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    Official Symbol
    itih6provided by Xenbase
    Official Full Name
    inter-alpha-trypsin inhibitor heavy chain family member 6provided by Xenbase
    Primary source
    Xenbase:XB-GENE-877173
    See related
    Ensembl:ENSXETG00000030443
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    itih5l
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (25063024..25106699)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (8547722..8591530, complement)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108645248 Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component Neighboring gene PHD finger protein 8 Neighboring gene HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Neighboring gene microRNA let-7f

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables peptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within hyaluronan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inter-alpha-trypsin inhibitor heavy chain H6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      25063024..25106699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031891861.1 → XP_031747721.1  inter-alpha-trypsin inhibitor heavy chain H6 isoform X1

      UniProtKB/TrEMBL
      A0A6I8R5G5, A0A6I8S7D8
      Related
      ENSXETP00000092712.2, ENSXETT00000083384.2
      Conserved Domains (4) summary
      cd01461
      Location:293 → 475
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      TIGR03788
      Location:62 → 638
      marine_srt_targ; marine proteobacterial sortase target protein
      pfam06668
      Location:971 → 1157
      ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus
      cl02699
      Location:47 → 161
      VIT; Vault protein inter-alpha-trypsin domain

    2. XM_031891862.1 → XP_031747722.1  inter-alpha-trypsin inhibitor heavy chain H6 isoform X2

      UniProtKB/TrEMBL
      A0A6I8R5G5, A0A6I8SLF0
      Related
      ENSXETP00000099057.2, ENSXETT00000099395.2
      Conserved Domains (4) summary
      cd01461
      Location:281 → 463
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      TIGR03788
      Location:50 → 626
      marine_srt_targ; marine proteobacterial sortase target protein
      pfam06668
      Location:959 → 1145
      ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus
      cl02699
      Location:35 → 149
      VIT; Vault protein inter-alpha-trypsin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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