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    c8b complement C8 beta chain [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100380076, updated on 8-Mar-2024

    Summary

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    Official Symbol
    c8bprovided by Xenbase
    Official Full Name
    complement C8 beta chainprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-998160
    See related
    Ensembl:ENSXETG00000011133
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (87469762..87489875)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (76088687..76108745, complement)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene Myb like, SWIRM and MPN domains 1 Neighboring gene OMA1 zinc metallopeptidase Neighboring gene Dab, reelin signal transducer, homolog 1 Neighboring gene filaggrin-2-like Neighboring gene complement C8 alpha chain Neighboring gene FYN binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    acts_upstream_of_or_within complement activation, alternative pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within complement activation, classical pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within killing of cells of another organism IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of membrane attack complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    complement component C8 beta chain
    Names
    complement component 8, beta polypeptide

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      87469762..87489875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002931587.4 → XP_002931633.2  complement component C8 beta chain

      UniProtKB/TrEMBL
      F6R5H7
      Related
      ENSXETP00000024355.4, ENSXETT00000024355.4
      Conserved Domains (3) summary
      smart00209
      Location:530 → 572
      TSP1; Thrombospondin type 1 repeats
      cd00112
      Location:107 → 137
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam01823
      Location:246 → 478
      MACPF; MAC/Perforin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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