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    leo1 LEO1 homolog, Paf1/RNA polymerase II complex component [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100135118, updated on 8-Mar-2024

    Summary

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    Official Symbol
    leo1provided by Xenbase
    Official Full Name
    LEO1 homolog, Paf1/RNA polymerase II complex componentprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-5828183
    See related
    Ensembl:ENSXETG00000020746
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    rdl
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (102295345..102308199, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (92334948..92347425, complement)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116409769 Neighboring gene mitogen-activated protein kinase 6 Neighboring gene tropomodulin 3 Neighboring gene uncharacterized LOC116409770 Neighboring gene tropomodulin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables RNA polymerase II C-terminal domain phosphoserine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryonic cranial skeleton morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within glial cell development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within heart development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within melanocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neural crest cell development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of transcription elongation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within spinal cord oligodendrocyte cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within xanthophore differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase-associated protein LEO1
    Names
    Leo1, Paf1/RNA polymerase II complex component, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      102295345..102308199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002936345.5 → XP_002936391.3  RNA polymerase-associated protein LEO1

      UniProtKB/TrEMBL
      A9JS07, F7EB62
      Related
      ENSXETP00000044838.5, ENSXETT00000044838.5
      Conserved Domains (2) summary
      COG5271
      Location:62 → 400
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam04004
      Location:417 → 579
      Leo1; Leo1-like protein
    Nucleotide Protein Strain
    Heading Accession and Version

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