lrrc15 leucine rich repeat containing 15 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: lrrc15provided by ZNC
Official Full Name: leucine rich repeat containing 15provided by ZNC
Primary source: ZFIN:ZDB-GENE-031113-8
See related: Ensembl:ENSDARG00000070792 AllianceGenome:ZFIN:ZDB-GENE-031113-8
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb894; zgc:158286
Summary: Predicted to enable Roundabout binding activity and heparin binding activity. Predicted to be involved in axon guidance and negative chemotaxis. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in cardiovascular system; hematopoietic system; ventral mesoderm; and yolk syncytial layer. Orthologous to human LRRC15 (leucine rich repeat containing 15). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (36459977..36463700)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (36482083..36485806)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fi75g08.x1 (e-PCR)
- UniSTS:197991

fj93a08.y1 (e-PCR)
- UniSTS:200354

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables Roundabout binding	IBA Inferred from Biological aspect of Ancestor more info
enables heparin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in axon guidance	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative chemotaxis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: leucine-rich repeat-containing protein 15

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080682.1 → NP_001074151.1 leucine-rich repeat-containing protein 15 precursor

See identical proteins and their annotated locations for NP_001074151.1

Status: PROVISIONAL

Source sequence(s)

BC129189

UniProtKB/TrEMBL

A1L1S0

Related

ENSDARP00000095023.3, ENSDART00000104248.4

Conserved Domains (6) summary

smart00013
Location:21 → 48

LRRNT; Leucine rich repeat N-terminal domain

cd00116
Location:163 → 253

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:171 → 194

LRR_RI; leucine-rich repeat [structural motif]

pfam12799
Location:241 → 280

LRR_4; Leucine Rich repeats (2 copies)

pfam13855
Location:170 → 229

LRR_8; Leucine rich repeat

cl15307
Location:418 → 467

TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain