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    IRF1 interferon regulatory factor 1 [ Bos taurus (cattle) ]

    Gene ID: 789216, updated on 3-Apr-2024

    Summary

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    Official Symbol
    IRF1provided by VGNC
    Official Full Name
    interferon regulatory factor 1provided by VGNC
    Primary source
    VGNC:VGNC:30270
    See related
    BGD:BT24247; Ensembl:ENSBTAG00000031231
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    IRF-1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (21938660..21946679)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene interleukin 13 Neighboring gene RAD50 double strand break repair protein Neighboring gene interleukin 5 Neighboring gene uncharacterized LOC132345719 Neighboring gene solute carrier family 22 member 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation of the bovine oxytocin receptor gene. Telgmann R, et al. Biol Reprod, 2003 Mar. PMID 12604656
    2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    3. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127194

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon regulatory factor 1
    Names
    interferon responsive factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191261.2 → NP_001178190.1  interferon regulatory factor 1

      See identical proteins and their annotated locations for NP_001178190.1

      Status: VALIDATED

      Source sequence(s)
      AM023700, BM256153, BM483600, CA034923, DT814919, DV811778
      UniProtKB/Swiss-Prot
      Q3SZP0, Q865L0
      UniProtKB/TrEMBL
      A0A140T8C0
      Related
      ENSBTAP00000041732.3, ENSBTAT00000044218.5
      Conserved Domains (1) summary
      pfam00605
      Location:7 → 112
      IRF; Interferon regulatory factor transcription factor

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      21938660..21946679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015472116.3 → XP_015327602.1  interferon regulatory factor 1 isoform X1

      Conserved Domains (1) summary
      pfam00605
      Location:7 → 112
      IRF; Interferon regulatory factor transcription factor
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3SZP0.1 GenPept UniProtKB/Swiss-Prot:Q3SZP0

    Gene LinkOut

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