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    gtf2e2.L general transcription factor IIE subunit 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 734303, updated on 11-Apr-2024

    Summary

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    Official Symbol
    gtf2e2.L
    Official Full Name
    general transcription factor IIE subunit 2 L homeolog
    Primary source
    Xenbase:XB-GENE-962390
    Locus tag
    XELAEV_18005888mg
    See related
    EnsemblRapid:ENSXLAG00005035808
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    gtf2e2
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    Genomic context

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    Location:
    chromosome: 1L
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (88768097..88798701, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (77862994..77892865, complement)

    Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene dynactin subunit 6 L homeolog Neighboring gene RNA binding protein with multiple splicing L homeolog Neighboring gene store-operated calcium entry-associated regulatory factor L homeolog Neighboring gene glutathione reductase L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural conservation of putative functional motifs between Xenopus and human TFIIE-beta. Ohkuma Y, et al. Nucleic Acids Res, 1992 Aug 25. PMID 1508726, Free PMC Article
    2. Conserved sequence motifs in the small subunit of human general transcription factor TFIIE. Sumimoto H, et al. Nature, 1991 Dec 5. PMID 1956404
    3. Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE. Ohkuma Y, et al. Nature, 1991 Dec 5. PMID 1956403
    4. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
    5. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC84983

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables TFIIH-class transcription factor complex binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIIE complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    general transcription factor IIE subunit 2
    Names
    TFIIE-beta
    general transcription factor IIE, polypeptide 2, beta 34kDa
    transcription initiation factor IIE subunit beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      88768097..88798701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041591096.1 → XP_041447030.1  general transcription factor IIE subunit 2

      UniProtKB/Swiss-Prot
      P29540, Q5FWM0
      UniProtKB/TrEMBL
      A0A1L8HVE9, A0A974DYH4
      Related
      ENSXLAP00005107115.1, ENSXLAT00005109226.1
      Conserved Domains (2) summary
      cd07977
      Location:65 → 143
      TFIIE_beta_winged_helix; TFIIE_beta_winged_helix domain, located at the central core region of TFIIE beta, with double-stranded DNA binding activity
      pfam18121
      Location:143 → 201
      TFA2_Winged_2; TFA2 Winged helix domain 2

    2. XM_041591091.1 → XP_041447025.1  general transcription factor IIE subunit 2

      UniProtKB/Swiss-Prot
      P29540, Q5FWM0
      UniProtKB/TrEMBL
      A0A1L8HVE9, A0A974DYH4
      Related
      ENSXLAP00005107105.1, ENSXLAT00005109217.1
      Conserved Domains (2) summary
      cd07977
      Location:65 → 143
      TFIIE_beta_winged_helix; TFIIE_beta_winged_helix domain, located at the central core region of TFIIE beta, with double-stranded DNA binding activity
      pfam18121
      Location:143 → 201
      TFA2_Winged_2; TFA2 Winged helix domain 2

    3. XM_041591092.1 → XP_041447026.1  general transcription factor IIE subunit 2

      UniProtKB/Swiss-Prot
      P29540, Q5FWM0
      UniProtKB/TrEMBL
      A0A1L8HVE9, A0A974DYH4
      Related
      ENSXLAP00005107096.1, ENSXLAT00005109208.1
      Conserved Domains (2) summary
      cd07977
      Location:65 → 143
      TFIIE_beta_winged_helix; TFIIE_beta_winged_helix domain, located at the central core region of TFIIE beta, with double-stranded DNA binding activity
      pfam18121
      Location:143 → 201
      TFA2_Winged_2; TFA2 Winged helix domain 2

    4. XM_041591098.1 → XP_041447032.1  general transcription factor IIE subunit 2

      UniProtKB/Swiss-Prot
      P29540, Q5FWM0
      UniProtKB/TrEMBL
      A0A1L8HVE9, A0A974DYH4
      Conserved Domains (2) summary
      cd07977
      Location:65 → 143
      TFIIE_beta_winged_helix; TFIIE_beta_winged_helix domain, located at the central core region of TFIIE beta, with double-stranded DNA binding activity
      pfam18121
      Location:143 → 201
      TFA2_Winged_2; TFA2 Winged helix domain 2

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001095787.1: Suppressed sequence

      Description
      NM_001095787.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P29540.1 GenPept UniProtKB/Swiss-Prot:P29540

    Gene LinkOut

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