EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: EDEM1provided by VGNC
Official Full Name: ER degradation enhancing alpha-mannosidase like protein 1provided by VGNC
Primary source: VGNC:VGNC:110370
See related: Ensembl:ENSMMUG00000065088
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	2	NC_041755.1 (136481011..136509794)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	2	NC_027894.1 (61297936..61326769, complement)

Chromosome 2 - NC_041755.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in endoplasmic reticulum mannose trimming	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mannose trimming involved in glycoprotein ERAD pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ER degradation-enhancing alpha-mannosidase-like protein 1

Names: ER degradation-enhancing alpha-mannosidase-like 1

NP_001252679.1

EC 3.2.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001265750.1 → NP_001252679.1 ER degradation-enhancing alpha-mannosidase-like protein 1

See identical proteins and their annotated locations for NP_001252679.1

Status: PROVISIONAL

Source sequence(s)

JV635551

UniProtKB/TrEMBL

F7F1M7, H9YUS9

Related

ENSMMUP00000075576.1, ENSMMUT00000103738.1

Conserved Domains (2) summary

pfam01532
Location:137 → 582

Glyco_hydro_47; Glycosyl hydrolase family 47

cl19311
Location:76 → 177

Urocanase; Urocanase