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    ADAM10 ADAM metallopeptidase domain 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701355, updated on 5-Mar-2024

    Summary

    Official Symbol
    ADAM10provided by VGNC
    Official Full Name
    ADAM metallopeptidase domain 10provided by VGNC
    Primary source
    VGNC:VGNC:69465
    See related
    Ensembl:ENSMMUG00000017507
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See ADAM10 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (35002933..35159892, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (35149252..35302292, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114679419 Neighboring gene lipase C, hepatic type Neighboring gene small nucleolar RNA U13 Neighboring gene putative heat shock protein HSP 90-beta 4 Neighboring gene small nucleolar RNA U3 Neighboring gene MINDY lysine 48 deubiquitinase 2

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in membrane protein ectodomain proteolysis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in synaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    disintegrin and metalloproteinase domain-containing protein 10
    XP_001097016.2
    XP_028706819.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      35002933..35159892 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001097016.4XP_001097016.2  disintegrin and metalloproteinase domain-containing protein 10 isoform X1

      UniProtKB/TrEMBL
      F6V4A7, G7MXJ7, H9EQI5
      Related
      ENSMMUP00000064836.1, ENSMMUT00000085071.1
      Conserved Domains (3) summary
      smart00050
      Location:466545
      DISIN; Homologues of snake disintegrins
      cd04270
      Location:220459
      ZnMc_TACE_like; Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
      pfam01562
      Location:46156
      Pep_M12B_propep; Reprolysin family propeptide
    2. XM_028850986.1XP_028706819.1  disintegrin and metalloproteinase domain-containing protein 10 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QFJ7, G7MXJ7
      Related
      ENSMMUP00000046817.2, ENSMMUT00000077486.2
      Conserved Domains (3) summary
      smart00050
      Location:392471
      DISIN; Homologues of snake disintegrins
      cd04270
      Location:146385
      ZnMc_TACE_like; Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
      pfam01562
      Location:282
      Pep_M12B_propep; Reprolysin family propeptide