TRAF7 TNF receptor associated factor 7 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: TRAF7provided by VGNC
Official Full Name: TNF receptor associated factor 7provided by VGNC
Primary source: VGNC:VGNC:79252
See related: Ensembl:ENSMMUG00000019223
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	20	NC_041773.1 (2187693..2209127)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	20	NC_027912.1 (2175168..2197695)

Chromosome 20 - NC_041773.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

SGC31214 (e-PCR)
- UniSTS:44364

MARC_4451-4452:966894632:1 (e-PCR)
- UniSTS:269389

RH71168 (e-PCR)
- UniSTS:18150

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in ribosomal large subunit assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleolus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TRAF7

Names: TNF receptor-associated factor 7, E3 ubiquitin protein ligase

NP_001248156.1

EC 2.3.2.27

XP_014980807.1

EC 2.3.2.27

XP_014980808.1

EC 2.3.2.27

XP_014980809.1

EC 2.3.2.27

XP_028696203.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261227.2 → NP_001248156.1 E3 ubiquitin-protein ligase TRAF7

See identical proteins and their annotated locations for NP_001248156.1

Status: PROVISIONAL

Source sequence(s)

JV048426

UniProtKB/TrEMBL

F6QNL6, G7NQV1

Related

ENSMMUP00000025265.2, ENSMMUT00000027006.4

Conserved Domains (6) summary

PRK03918
Location:283 → 373

PRK03918; DNA double-strand break repair ATPase Rad50

cd00200
Location:388 → 668

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:443 → 477

7WD40; WD40 repeat [structural motif]

cd16644
Location:129 → 165

mRING-HC-C3HC3D_TRAF7; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 7 (TRAF7) and similar proteins

cl17044
Location:282 → 322

DD_cGKI; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I

cl19105
Location:207 → 281

Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041773.1 Reference Mmul_10 Primary Assembly

Range

2187693..2209127

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015125321.2 → XP_014980807.1 E3 ubiquitin-protein ligase TRAF7 isoform X2

UniProtKB/TrEMBL

G7NQV1

Conserved Domains (6) summary

PRK03918
Location:281 → 371

PRK03918; DNA double-strand break repair ATPase Rad50

cd00200
Location:386 → 666

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:441 → 475

7WD40; WD40 repeat [structural motif]

cd16644
Location:129 → 165

mRING-HC-C3HC3D_TRAF7; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 7 (TRAF7) and similar proteins

cl17044
Location:280 → 320

DD_cGKI; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I

cl19105
Location:207 → 279

Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
XM_015125322.2 → XP_014980808.1 E3 ubiquitin-protein ligase TRAF7 isoform X3

UniProtKB/TrEMBL

G7NQV1

Conserved Domains (6) summary

cl17044
Location:243 → 283

DD_cGKI; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I

smart00184
Location:92 → 124

RING; Ring finger

COG2319
Location:341 → 629

WD40; WD40 repeat [General function prediction only]

cd00200
Location:349 → 629

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:404 → 438

7WD40; WD40 repeat [structural motif]

cl19105
Location:168 → 241

Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
XM_015125323.2 → XP_014980809.1 E3 ubiquitin-protein ligase TRAF7 isoform X4

UniProtKB/TrEMBL

G7NQV1

Conserved Domains (6) summary

PRK03918
Location:242 → 332

PRK03918; DNA double-strand break repair ATPase Rad50

cd00200
Location:347 → 627

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:402 → 436

7WD40; WD40 repeat [structural motif]

cd16644
Location:90 → 126

mRING-HC-C3HC3D_TRAF7; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 7 (TRAF7) and similar proteins

cl17044
Location:241 → 281

DD_cGKI; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I

cl19105
Location:168 → 240

Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
XM_028840370.1 → XP_028696203.1 E3 ubiquitin-protein ligase TRAF7 isoform X1

UniProtKB/TrEMBL

F6QNL6, G7NQV1

Conserved Domains (6) summary

PRK03918
Location:283 → 373

PRK03918; DNA double-strand break repair ATPase Rad50

cd00200
Location:388 → 668

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:443 → 477

7WD40; WD40 repeat [structural motif]

cd16644
Location:129 → 165

mRING-HC-C3HC3D_TRAF7; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 7 (TRAF7) and similar proteins

cl17044
Location:282 → 322

DD_cGKI; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I

cl19105
Location:207 → 281

Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...