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    PAPOLA poly(A) polymerase alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 641447, updated on 11-Apr-2024

    Summary

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    Official Symbol
    PAPOLAprovided by VGNC
    Official Full Name
    poly(A) polymerase alphaprovided by VGNC
    Primary source
    VGNC:VGNC:84415
    See related
    Ensembl:ENSMMUG00000018610
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (158696220..158761692)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (158783639..158849078)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene GSK3B interacting protein Neighboring gene phosphatidylethanolamine-binding protein 1 pseudogene Neighboring gene adenylate kinase 7 Neighboring gene uncharacterized LOC114679639 Neighboring gene ubiquitin-fold modifier-conjugating enzyme 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables poly(A) RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    poly(A) polymerase alpha
    NP_001252826.1
    XP_014999919.1
    XP_014999920.1
    XP_014999921.1
    XP_014999922.1
    XP_028705982.1
    XP_028705983.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265897.1 → NP_001252826.1  poly(A) polymerase alpha

      See identical proteins and their annotated locations for NP_001252826.1

      Status: PROVISIONAL

      Source sequence(s)
      JV046004
      UniProtKB/TrEMBL
      G7MW43, H9FP34
      Related
      ENSMMUP00000053333.1, ENSMMUT00000064078.2
      Conserved Domains (3) summary
      pfam04926
      Location:366 → 495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:21 → 363
      PAP_central; Poly(A) polymerase central domain
      cl26091
      Location:501 → 646
      MotB_plug; Membrane MotB of proton-channel complex MotA/MotB

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      158696220..158761692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144436.2 → XP_014999922.1  poly(A) polymerase alpha isoform X6

      UniProtKB/TrEMBL
      F6QV78, G7MW43
      Related
      ENSMMUP00000032588.3, ENSMMUT00000039510.3
      Conserved Domains (3) summary
      PTZ00418
      Location:9 → 567
      PTZ00418; Poly(A) polymerase; Provisional
      pfam04926
      Location:366 → 495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:21 → 363
      PAP_central; Poly(A) polymerase central domain

    2. XM_015144433.2 → XP_014999919.1  poly(A) polymerase alpha isoform X1

      UniProtKB/TrEMBL
      G7MW43
      Conserved Domains (3) summary
      pfam04926
      Location:366 → 495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:21 → 363
      PAP_central; Poly(A) polymerase central domain
      cl26091
      Location:501 → 645
      MotB_plug; Membrane MotB of proton-channel complex MotA/MotB

    3. XM_015144434.2 → XP_014999920.1  poly(A) polymerase alpha isoform X2

      UniProtKB/TrEMBL
      A0A1D5QFG2, G7MW43, H9FP32
      Related
      ENSMMUP00000046782.2, ENSMMUT00000076856.2
      Conserved Domains (3) summary
      PRK12799
      Location:501 → 646
      motB; flagellar motor protein MotB; Reviewed
      pfam04926
      Location:366 → 495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:21 → 363
      PAP_central; Poly(A) polymerase central domain

    4. XM_015144435.2 → XP_014999921.1  poly(A) polymerase alpha isoform X4

      UniProtKB/TrEMBL
      F6QV47, G7MW43
      Related
      ENSMMUP00000032591.3, ENSMMUT00000039513.3
      Conserved Domains (3) summary
      PRK12799
      Location:501 → 646
      motB; flagellar motor protein MotB; Reviewed
      pfam04926
      Location:366 → 495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:21 → 363
      PAP_central; Poly(A) polymerase central domain

    5. XM_028850149.1 → XP_028705982.1  poly(A) polymerase alpha isoform X3

      UniProtKB/TrEMBL
      G7MW43
      Conserved Domains (3) summary
      PRK12799
      Location:501 → 645
      motB; flagellar motor protein MotB; Reviewed
      pfam04926
      Location:366 → 495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:21 → 363
      PAP_central; Poly(A) polymerase central domain

    6. XM_028850150.1 → XP_028705983.1  poly(A) polymerase alpha isoform X5

      UniProtKB/TrEMBL
      G7MW43
      Conserved Domains (3) summary
      PRK12799
      Location:501 → 645
      motB; flagellar motor protein MotB; Reviewed
      pfam04926
      Location:366 → 495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:21 → 363
      PAP_central; Poly(A) polymerase central domain
    Nucleotide Protein
    Heading Accession and Version

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