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    PBX2 PBX homeobox 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 607695, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PBX2provided by VGNC
    Official Full Name
    PBX homeobox 2provided by VGNC
    Primary source
    VGNC:VGNC:44287
    See related
    Ensembl:ENSCAFG00845016393
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    PBX2P1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (1715867..1720898, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (1711340..1716366, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (1710814..1715841, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (1578901..1583922, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (1644490..1649520, complement)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene EGF like domain multiple 8 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 1 Neighboring gene ring finger protein 5 Neighboring gene advanced glycosylation end-product specific receptor Neighboring gene butyrophilin-like protein 1 Neighboring gene G protein signaling modulator 3 Neighboring gene notch receptor 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryonic organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in eye development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-B-cell leukemia transcription factor 2; LOW QUALITY PROTEIN: pre-B-cell leukemia transcription factor 2
    Names
    pre-B-cell leukemia homeobox 2 pseudogene 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      1715867..1720898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038683079.1 → XP_038539007.1  pre-B-cell leukemia transcription factor 2

      UniProtKB/TrEMBL
      A0A8C0JLM0, A0A8C0T2Z3, A0A8I3NWU6
      Related
      ENSCAFP00845022902.1, ENSCAFT00845029118.1
      Conserved Domains (2) summary
      cd00086
      Location:245 → 305
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:50 → 243
      PBC; PBC domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      1578901..1583922 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038491398.1 → XP_038347326.1  pre-B-cell leukemia transcription factor 2

      Conserved Domains (2) summary
      cd00086
      Location:245 → 305
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:50 → 243
      PBC; PBC domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      1644490..1649520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038617491.1 → XP_038473419.1  LOW QUALITY PROTEIN: pre-B-cell leukemia transcription factor 2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      1710814..1715841 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038553615.1 → XP_038409543.1  pre-B-cell leukemia transcription factor 2

      UniProtKB/TrEMBL
      A0A8C0JLM0, A0A8C0T2Z3, A0A8I3NWU6
      Conserved Domains (2) summary
      cd00086
      Location:245 → 305
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:50 → 243
      PBC; PBC domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      1711340..1716366 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_845159.5 → XP_850252.3  pre-B-cell leukemia transcription factor 2

      UniProtKB/TrEMBL
      A0A8C0JLM0, A0A8C0T2Z3, A0A8I3NWU6
      Conserved Domains (2) summary
      cd00086
      Location:245 → 305
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:50 → 243
      PBC; PBC domain
    Nucleotide Protein
    Heading Accession and Version

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