snx17 sorting nexin 17 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snx17provided by ZNC
Official Full Name: sorting nexin 17provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9475
See related: Ensembl:ENSDARG00000091418 AllianceGenome:ZFIN:ZDB-GENE-030131-9475
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb67g03; wu:fb67g09; wu:fc27g08; wu:fj81d04; si:ch211-101l18.2
Summary: Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in intracellular protein transport. Predicted to act upstream of or within protein transport and signal transduction. Predicted to be located in cytoplasmic vesicle and cytosol. Predicted to be active in early endosome. Is expressed in brain; eye; liver; and pancreas. Orthologous to human SNX17 (sorting nexin 17). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (19436186..19511646, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (19536604..19612057, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj81d04.x1 (e-PCR)
- UniSTS:199992

fb67g09 (e-PCR)
- UniSTS:189076

AI558899 (e-PCR)
- UniSTS:206252

fc27g08.x1 (e-PCR)
- UniSTS:187886

fb67g03.y1 (e-PCR)
- UniSTS:190960

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in endocytic recycling	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasmic vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
is_active_in early endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sorting nexin-17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045157.3 → NP_001038622.2 sorting nexin-17

See identical proteins and their annotated locations for NP_001038622.2

Status: PROVISIONAL

Source sequence(s)

BC162993

UniProtKB/TrEMBL

A0A0R4ITX6

Related

ENSDARP00000137695.1, ENSDART00000168521.2

Conserved Domains (3) summary

cd06885
Location:2 → 105

PX_SNX17_31; The phosphoinositide binding Phox Homology domain of Sorting Nexins 17 and 31

cd13337
Location:268 → 388

FERM-like_C_SNX17; Atypical FERM-like domain C-lobe of Sorting nexin 17

cl00155
Location:115 → 185

UBQ; Ubiquitin-like proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007131.7 Reference GRCz11 Primary Assembly

Range

19436186..19511646 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009294624.2 → XP_009292899.1 sorting nexin-17 isoform X1

See identical proteins and their annotated locations for XP_009292899.1

UniProtKB/Swiss-Prot

B3DI45, Q5RID7

Related

ENSDARP00000040190.4, ENSDART00000040191.6

Conserved Domains (3) summary

cd06885
Location:2 → 105

PX_SNX17_31; The phosphoinositide binding Phox Homology domain of Sorting Nexins 17 and 31

cd13337
Location:268 → 388

FERM-like_C_SNX17; Atypical FERM-like domain C-lobe of Sorting nexin 17

cl00155
Location:115 → 185

UBQ; Ubiquitin-like proteins
XM_009294625.2 → XP_009292900.1 sorting nexin-17 isoform X2

UniProtKB/TrEMBL

A0A8M3B409

Conserved Domains (1) summary

cd13337
Location:55 → 175

FERM-like_C_SNX17; Atypical FERM-like domain C-lobe of Sorting nexin 17