hpse heparanase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hpseprovided by ZNC
Official Full Name: heparanaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041111-200
See related: Ensembl:ENSDARG00000063634 AllianceGenome:ZFIN:ZDB-GENE-041111-200
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7144134
Summary: Predicted to enable hydrolase activity, acting on glycosyl bonds. Predicted to be located in membrane. Predicted to be active in extracellular matrix. Orthologous to human HPSE (heparanase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (19347655..19361313)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (19311019..19324677)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in angiogenesis involved in wound healing	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell-matrix adhesion	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: heparanase

NP_001038470.1

EC 3.2.1.166

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045005.1 → NP_001038470.1 heparanase precursor

Status: PROVISIONAL

Source sequence(s)

BX649525

UniProtKB/TrEMBL

A0A8M1N9R1, Q1LVP9

Related

ENSDARP00000087587.5, ENSDART00000093155.6

Conserved Domains (1) summary

pfam03662
Location:37 → 369

Glyco_hydro_79n; Glycosyl hydrolase family 79, N-terminal domain