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    mmd2a monocyte to macrophage differentiation-associated 2a [ Danio rerio (zebrafish) ]

    Gene ID: 558749, updated on 27-Mar-2024

    Summary

    Official Symbol
    mmd2aprovided by ZNC
    Official Full Name
    monocyte to macrophage differentiation-associated 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081104-52
    See related
    Ensembl:ENSDARG00000087446 AllianceGenome:ZFIN:ZDB-GENE-081104-52
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mmd2; paqr10; si:dkey-21n8.8
    Summary
    Acts upstream of or within heart morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including nervous system; notochord; pectoral fin; vasculature; and ventral mesoderm. Orthologous to human MMD2 (monocyte to macrophage differentiation associated 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (40841984..40870521)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (40700126..40728663)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene actin related protein 2/3 complex, subunit 1B Neighboring gene WD repeat domain, phosphoinositide interacting 2 Neighboring gene adaptor related protein complex 5 subunit zeta 1 Neighboring gene forkhead box K1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables pore-forming activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within heart morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    monocyte to macrophage differentiation factor 2a
    Names
    monocyte to macrophage differentiation-associated 2
    progestin and adipoQ receptor 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001174058.1NP_001167529.1  monocyte to macrophage differentiation factor 2a

      See identical proteins and their annotated locations for NP_001167529.1

      Status: VALIDATED

      Source sequence(s)
      GU556567
      UniProtKB/TrEMBL
      A0A8M1NUG7, D3YLD4, F6P7K7
      Related
      ENSDARP00000107681.3, ENSDART00000126096.3
      Conserved Domains (1) summary
      cl03831
      Location:31231
      HlyIII; Haemolysin-III related

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      40841984..40870521
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)