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    DLK2 delta like non-canonical Notch ligand 2 [ Bos taurus (cattle) ]

    Gene ID: 540262, updated on 13-Apr-2024

    Summary

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    Official Symbol
    DLK2provided by VGNC
    Official Full Name
    delta like non-canonical Notch ligand 2provided by VGNC
    Primary source
    VGNC:VGNC:28093
    See related
    BGD:BT30070; Ensembl:ENSBTAG00000005850
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    DLK-2
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (17008894..17014424, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene RWD domain-containing protein 1-like Neighboring gene ATP binding cassette subfamily C member 10 Neighboring gene uncharacterized LOC132343619 Neighboring gene tight junction associated protein 1 Neighboring gene leucine rich repeat containing 73

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC151582

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Notch binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein delta homolog 2
    Names
    EGF-like protein 9
    EGF-like-domain, multiple 9
    epidermal growth factor-like protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083494.1 → NP_001076963.1  protein delta homolog 2 precursor

      See identical proteins and their annotated locations for NP_001076963.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123884
      UniProtKB/Swiss-Prot
      A4FV93
      Related
      ENSBTAP00000007690.6, ENSBTAT00000007690.7
      Conserved Domains (1) summary
      cd00054
      Location:89 → 129
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      17008894..17014424 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059880419.1 → XP_059736402.1  protein delta homolog 2 isoform X2

    2. XM_005223483.4 → XP_005223540.1  protein delta homolog 2 isoform X1

      See identical proteins and their annotated locations for XP_005223540.1

      UniProtKB/Swiss-Prot
      A4FV93
      Related
      ENSBTAP00000083876.1, ENSBTAT00000116863.1
      Conserved Domains (1) summary
      cd00054
      Location:89 → 129
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

    3. XM_005223484.5 → XP_005223541.1  protein delta homolog 2 isoform X1

      See identical proteins and their annotated locations for XP_005223541.1

      UniProtKB/Swiss-Prot
      A4FV93
      Conserved Domains (1) summary
      cd00054
      Location:89 → 129
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A4FV93.1 GenPept UniProtKB/Swiss-Prot:A4FV93

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