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    CFL2 cofilin 2 [ Bos taurus (cattle) ]

    Gene ID: 539332, updated on 5-Mar-2024

    Summary

    Official Symbol
    CFL2provided by VGNC
    Official Full Name
    cofilin 2provided by VGNC
    Primary source
    VGNC:VGNC:27254
    See related
    BGD:BT30278; Ensembl:ENSBTAG00000015053
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    Location:
    chromosome: 21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (45097671..45101862, complement)

    Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U3 Neighboring gene sorting nexin 6 Neighboring gene cleavage and polyadenylation specificity factor subunit 5-like Neighboring gene bromodomain adjacent to zinc finger domain 1A Neighboring gene uncharacterized LOC132343371

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC140740

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in actin filament fragmentation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in actin filament severing IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin cortical patch IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    cofilin-2
    Names
    cofilin 2 (muscle)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076154.2NP_001069622.1  cofilin-2

      See identical proteins and their annotated locations for NP_001069622.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118390
      UniProtKB/Swiss-Prot
      Q148F1
      Related
      ENSBTAP00000020036.3, ENSBTAT00000020036.4
      Conserved Domains (1) summary
      cd11286
      Location:3153
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      45097671..45101862 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879146.1XP_059735129.1  cofilin-2 isoform X1